U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    zp3 zona pellucida glycoprotein 3 [ Danio rerio (zebrafish) ]

    Gene ID: 30594, updated on 27-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    zp3provided by ZNC
    Official Full Name
    zona pellucida glycoprotein 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-991129-7
    See related
    Ensembl:ENSDARG00000114958 AllianceGenome:ZFIN:ZDB-GENE-991129-7
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zp3.2
    Summary
    Predicted to be a structural constituent of egg coat. Predicted to act upstream of or within binding activity of sperm to zona pellucida and egg coat formation. Predicted to be located in extracellular region and plasma membrane. Is expressed in gamete; gonad; immature gonad; oocyte; and ovary. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 17
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (2580539..2584416, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (2404153..2408030, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene zgc:173556 Neighboring gene zona pellucida glycoprotein 3, tandem duplicate 1 Neighboring gene zona pellucida glycoprotein 3, tandem duplicate 2 Neighboring gene zona pellucida sperm-binding protein 3-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Generation of oocyte-specifically expressed cre transgenic zebrafish for female germline excision of loxP-flanked transgene. Liu X, et al. Dev Dyn, 2008 Oct. PMID 18816824
    2. Transgene driving GFP expression from the promoter of the zona pellucida gene zpc is expressed in oocytes and provides an early marker for gonad differentiation in zebrafish. Onichtchouk D, et al. Dev Dyn, 2003 Nov. PMID 14579378
    3. Evolution and nomenclature of the zona pellucida gene family. Spargo SC, et al. Biol Reprod, 2003 Feb. PMID 12533396
    4. A transgenic zebrafish model of targeted oocyte ablation and de novo oogenesis. White YA, et al. Dev Dyn, 2011 Aug. PMID 21761478
    5. Purification and characterization of zebrafish hatching enzyme - an evolutionary aspect of the mechanism of egg envelope digestion. Sano K, et al. FEBS J, 2008 Dec. PMID 19021768

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Regulation of zebrafish zona pellucida gene activity in developing oocytes.
      Title: Regulation of zebrafish zona pellucida gene activity in developing oocytes.
    2. The new transgenic line not only provided a convenient living marker for monitoring female gonad development, but also demonstrated that a single zp3 gene promoter is sufficient for oocyte-specific transcription.
      Title: Tandem-repeated Zebrafish zp3 genes possess oocyte-specific promoters and are insensitive to estrogen induction.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of egg coat IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in binding of sperm to zona pellucida IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in egg coat formation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of acrosome reaction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in egg coat IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    zona pellucida sperm-binding protein 3
    Names
    zona pellucida glycoprotein 3.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131331.1 → NP_571406.1  zona pellucida sperm-binding protein 3 precursor

      See identical proteins and their annotated locations for NP_571406.1

      Status: PROVISIONAL

      Source sequence(s)
      AF095457
      UniProtKB/TrEMBL
      Q9PWC7
      Related
      ENSDARP00000005402.7, ENSDART00000013506.7
      Conserved Domains (2) summary
      smart00241
      Location:117 → 372
      ZP; Zona pellucida (ZP) domain
      pfam00100
      Location:234 → 371
      Zona_pellucida; Zona pellucida-like domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      2580539..2584416 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.