Ms4a14 membrane spanning 4-domains A14 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ms4a14provided by RGD
Official Full Name: membrane spanning 4-domains A14provided by RGD
Primary source: RGD:727900
See related: Ensembl:ENSRNOG00000025805 AllianceGenome:RGD:727900
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Sp3111
Summary: Predicted to be integral component of membrane. Orthologous to human MS4A14 (membrane spanning 4-domains A14). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 326.3) See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (217374325..217389839, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (207949423..207964937, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (227471441..227486953, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Report the cDNA isolation of Ms4a14 in adult rat testes and suggest roles in fertilization and zygote division.
Title: cDNA cloning and localization of Sp3111 (also called Ms4a14) in the rat testis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cell surface receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: membrane-spanning 4-domains subfamily A member 14

Names: membrane-spanning 4-domains, subfamily A, member 14; sperm protein 3111; sperm protein SSP3111

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_181082.2 → NP_851596.1 membrane-spanning 4-domains subfamily A member 14

See identical proteins and their annotated locations for NP_851596.1

Status: PROVISIONAL

Source sequence(s)

AY258290

UniProtKB/TrEMBL

A6I088, G3V955, Q80WF0

Related

ENSRNOP00000036155.2, ENSRNOT00000035812.4

Conserved Domains (3) summary

pfam04103
Location:44 → 140

CD20; CD20-like family

pfam05934
Location:411 → 564

MCLC; Mid-1-related chloride channel (MCLC)

pfam15240
Location:439 → 624

Pro-rich; Proline-rich