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    PLA2G15 phospholipase A2 group XV [ Bos taurus (cattle) ]

    Gene ID: 282271, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PLA2G15provided by VGNC
    Official Full Name
    phospholipase A2 group XVprovided by VGNC
    Primary source
    VGNC:VGNC:32956
    See related
    BGD:BT10554; Ensembl:ENSBTAG00000007512
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    ACS; LLPL; LPLA2; LYPLA3
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (35624573..35640098)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene nuclear factor of activated T cells 3 Neighboring gene U6 spliceosomal RNA Neighboring gene epithelial splicing regulatory protein 2 Neighboring gene small ribosomal subunit protein uS19-like Neighboring gene solute carrier family 7 member 6 Neighboring gene solute carrier family 7 member 6 opposite strand Neighboring gene small nucleolar RNA SNORA19 Neighboring gene protein arginine methyltransferase 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2 with transacylase activity. Abe A, et al. J Biol Chem, 1998 Apr 3. PMID 9525960
    2. Cloning and characterization of a lysosomal phospholipase A2, 1-O-acylceramide synthase. Hiraoka M, et al. J Biol Chem, 2002 Mar 22. PMID 11790796
    3. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-independent phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylcholine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phospholipase A2 group XV
    Names
    1-O-acylceramide synthase
    LCAT-like lysophospholipase
    group XV phospholipase A2
    lysophospholipase 3 (lysosomal phospholipase A2)
    lysosomal phospholipase A and acyltransferase
    lysosomal phospholipase A2
    NP_776985.2
    XP_059732497.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174560.2 → NP_776985.2  phospholipase A2 group XV precursor

      See identical proteins and their annotated locations for NP_776985.2

      Status: PROVISIONAL

      Source sequence(s)
      BT021838
      UniProtKB/Swiss-Prot
      Q8WMP9
      Related
      ENSBTAP00000009888.2, ENSBTAT00000009888.4
      Conserved Domains (1) summary
      cl21494
      Location:79 → 391
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35624573..35640098
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876514.1 → XP_059732497.1  phospholipase A2 group XV isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WMP9.1 GenPept UniProtKB/Swiss-Prot:Q8WMP9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.