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    GNB2 G protein subunit beta 2 [ Bos taurus (cattle) ]

    Gene ID: 281202, updated on 4-Apr-2024

    Summary

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    Official Symbol
    GNB2provided by VGNC
    Official Full Name
    G protein subunit beta 2provided by VGNC
    Primary source
    VGNC:VGNC:29459
    See related
    BGD:BT10758; Ensembl:ENSBTAG00000006495
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    HG2C1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (35909868..35915046, complement)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2 Neighboring gene GRB10 interacting GYF protein 1 Neighboring gene uncharacterized LOC132343875 Neighboring gene actin like 6B Neighboring gene uncharacterized LOC101903098 Neighboring gene uncharacterized LOC104970491 Neighboring gene transferrin receptor 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A second form of the beta subunit of signal-transducing G proteins. Gao B, et al. Proc Natl Acad Sci U S A, 1987 Sep. PMID 3114742, Free PMC Article
    2. Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning. Fong HK, et al. Proc Natl Acad Sci U S A, 1987 Jun. PMID 3108879, Free PMC Article
    3. Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA. von Weizsäcker E, et al. Biochem Biophys Res Commun, 1992 Feb 28. PMID 1543505
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of heterotrimeric G-protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
    Names
    g protein subunit beta-2
    guanine nucleotide binding protein (G protein),beta polypeptide 2
    heterotrimeric guanine nucleotide-binding protein 2C1
    transducin beta chain 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001097561.1 → NP_001091030.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

      See identical proteins and their annotated locations for NP_001091030.1

      Status: PROVISIONAL

      Source sequence(s)
      BC140489
      UniProtKB/Swiss-Prot
      A5D7A9, P11017
      Related
      ENSBTAP00000008508.4, ENSBTAT00000008508.6
      Conserved Domains (2) summary
      cd00200
      Location:48 → 340
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:58 → 95
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35909868..35915046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11017.3 GenPept UniProtKB/Swiss-Prot:P11017

    Gene LinkOut

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