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    Arhgap18 Rho GTPase activating protein 18 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101726249, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Arhgap18
    Gene description
    Rho GTPase activating protein 18
    Locus tag
    GW7_21853
    See related
    Ensembl:ENSHGLG00000019278
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Arhgap18 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624753.1 (3854364..4034307, complement)

    NW_004624753.1Genomic Context describing neighboring genes Neighboring gene laminin subunit alpha 2 Neighboring gene uncharacterized LOC110349469 Neighboring gene rho GTPase-activating protein 20 pseudogene Neighboring gene uncharacterized LOC110349470 Neighboring gene U6 snRNA-associated Sm-like protein LSm3 pseudogene Neighboring gene meiotic nuclear division protein 1 homolog Neighboring gene transmembrane protein 244

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624753 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624753.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      3854364..4034307 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004845972.2 → XP_004846029.1  rho GTPase-activating protein 18 isoform X4

      UniProtKB/TrEMBL
      G5C768
      Conserved Domains (1) summary
      cd04391
      Location:278 → 491
      RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...

    2. XM_004845971.3 → XP_004846028.1  rho GTPase-activating protein 18 isoform X3

      UniProtKB/TrEMBL
      G5C768
      Conserved Domains (1) summary
      cd04391
      Location:298 → 511
      RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...

    3. XM_004845968.3 → XP_004846025.1  rho GTPase-activating protein 18 isoform X1

      UniProtKB/TrEMBL
      G5C768
      Related
      ENSHGLP00000027106.1, ENSHGLT00000027346.1
      Conserved Domains (1) summary
      cd04391
      Location:325 → 538
      RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...

    4. XM_004845970.2 → XP_004846027.1  rho GTPase-activating protein 18 isoform X2

      UniProtKB/TrEMBL
      G5C768
      Conserved Domains (1) summary
      cd04391
      Location:299 → 512
      RhoGAP_ARHGAP18; RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their ...
    Nucleotide Protein
    Heading Accession and Version

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