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    Hes5 hes family bHLH transcription factor 5 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101724400, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Hes5
    Gene description
    hes family bHLH transcription factor 5
    See related
    Ensembl:ENSHGLG00000017018
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624818.1 (7516279..7517654)

    NW_004624818.1Genomic Context describing neighboring genes Neighboring gene membrane metalloendopeptidase like 1 Neighboring gene peroxiredoxin like 2B Neighboring gene TNF receptor superfamily member 14 Neighboring gene pantothenate kinase 4 (inactive) Neighboring gene phospholipase C eta 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624818 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anterior/posterior pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor HES-5
    Names
    hairy and enhancer of split 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624818.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      7516279..7517654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004863788.3 → XP_004863845.1  transcription factor HES-5

      Related
      ENSHGLP00000023869.1, ENSHGLT00000024087.1
      Conserved Domains (2) summary
      cd00083
      Location:14 → 71
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cl02638
      Location:87 → 121
      Hairy_orange; Hairy Orange
    Nucleotide Protein
    Heading Accession and Version

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