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    Lrfn2 leucine rich repeat and fibronectin type III domain containing 2 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101722867, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Lrfn2
    Gene description
    leucine rich repeat and fibronectin type III domain containing 2
    Locus tag
    GW7_13653
    See related
    Ensembl:ENSHGLG00000017144
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624754.1 (18054520..18201529)

    NW_004624754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110349608 Neighboring gene zinc finger protein ZPR1 pseudogene Neighboring gene rho GTPase-activating protein 12-like Neighboring gene uncharacterized LOC110349609 Neighboring gene molybdenum cofactor synthesis 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624754 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat and fibronectin type-III domain-containing protein 2
    Names
    Leucine-rich repeat and fibronectin type-III domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624754.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      18054520..18201529
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004846627.2 → XP_004846684.1  leucine-rich repeat and fibronectin type-III domain-containing protein 2

      See identical proteins and their annotated locations for XP_004846684.1

      UniProtKB/TrEMBL
      G5APJ3
      Related
      ENSHGLP00000024053.1, ENSHGLT00000024272.1
      Conserved Domains (7) summary
      smart00082
      Location:242 → 286
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:298 → 376
      IG_like; Immunoglobulin like
      cd00116
      Location:27 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:54 → 77
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00041
      Location:428 → 493
      fn3; Fibronectin type III domain
      pfam13855
      Location:76 → 136
      LRR_8; Leucine rich repeat
      cl11960
      Location:303 → 376
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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