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    Nfatc4 nuclear factor of activated T cells 4 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101718532, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Nfatc4
    Gene description
    nuclear factor of activated T cells 4
    See related
    Ensembl:ENSHGLG00000001382
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624820.1 (8136231..8145395, complement)

    NW_004624820.1Genomic Context describing neighboring genes Neighboring gene NYN domain and retroviral integrase containing Neighboring gene uncharacterized LOC110345658 Neighboring gene serine-threonine kinase receptor-associated protein pseudogene Neighboring gene 60S ribosomal protein L23a pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624820 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor of activated T-cells, cytoplasmic 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624820.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      8136231..8145395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004864078.2 → XP_004864135.1  nuclear factor of activated T-cells, cytoplasmic 4

      UniProtKB/TrEMBL
      A0A0P6JDG6, G5B272
      Related
      ENSHGLP00000001814.1, ENSHGLT00000001860.1
      Conserved Domains (2) summary
      cd07881
      Location:407 → 580
      RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
      cd01178
      Location:585 → 685
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
    Nucleotide Protein
    Heading Accession and Version

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