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    Pcca propionyl-CoA carboxylase subunit alpha [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101711474, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Pcca
    Gene description
    propionyl-CoA carboxylase subunit alpha
    See related
    Ensembl:ENSHGLG00000011057
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Pcca in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624793.1 (10691224..11099905, complement)

    NW_004624793.1Genomic Context describing neighboring genes Neighboring gene transmembrane O-mannosyltransferase targeting cadherins 4 Neighboring gene MICOS complex subunit MIC27 pseudogene Neighboring gene gamma-glutamylamine cyclotransferase Neighboring gene biorientation of chromosomes in cell division protein 1 pseudogene Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene uncharacterized LOC110344686 Neighboring gene uncharacterized LOC106010573 Neighboring gene Zic family member 2 Neighboring gene Zic family member 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624793 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables propionyl-CoA carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    propionyl-CoA carboxylase alpha chain, mitochondrial
    Names
    propionyl-CoA carboxylase alpha chain
    propionyl-CoA carboxylase alpha subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624793.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      10691224..11099905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021239372.1 → XP_021095031.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X2

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      cl27361
      Location:63 → 731
      Biotin_carb_C; Biotin carboxylase C-terminal domain

    2. XM_021239377.1 → XP_021095036.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X9

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      cl27361
      Location:62 → 662
      Biotin_carb_C; Biotin carboxylase C-terminal domain

    3. XM_021239374.1 → XP_021095033.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X5

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      cl27361
      Location:63 → 718
      Biotin_carb_C; Biotin carboxylase C-terminal domain

    4. XM_021239375.1 → XP_021095034.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X7

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      cl27361
      Location:63 → 675
      Biotin_carb_C; Biotin carboxylase C-terminal domain

    5. XM_013077272.2 → XP_012932726.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X6

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (5) summary
      cd06850
      Location:624 → 690
      biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
      smart00878
      Location:397 → 477
      Biotin_carb_C; Biotin carboxylase C-terminal domain
      COG4770
      Location:63 → 691
      PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
      pfam00289
      Location:63 → 171
      CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
      pfam02786
      Location:176 → 383
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    6. XM_004858612.3 → XP_004858669.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A0N8EUZ8, G5B1U5
      Related
      ENSHGLP00000015463.1, ENSHGLT00000015623.1
      Conserved Domains (5) summary
      cd06850
      Location:661 → 727
      biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
      smart00878
      Location:397 → 504
      Biotin_carb_C; Biotin carboxylase C-terminal domain
      COG4770
      Location:63 → 728
      PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]
      pfam00289
      Location:63 → 171
      CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
      pfam02786
      Location:176 → 383
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    7. XM_021239373.1 → XP_021095032.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X4

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      COG4770
      Location:63 → 724
      PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]

    8. XM_021239371.1 → XP_021095030.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      COG4770
      Location:63 → 757
      PccA; Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid transport and metabolism]

    9. XM_021239376.1 → XP_021095035.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X8

      UniProtKB/TrEMBL
      G5B1U5
      Conserved Domains (1) summary
      cl27361
      Location:63 → 621
      Biotin_carb_C; Biotin carboxylase C-terminal domain

    10. XM_021239378.1 → XP_021095037.1  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X10

      Conserved Domains (1) summary
      cl27361
      Location:63 → 570
      Biotin_carb_C; Biotin carboxylase C-terminal domain

    RNA

    1. XR_002387410.1 RNA Sequence

    2. XR_002387412.1 RNA Sequence

    3. XR_002387411.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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