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    Mta3 metastasis associated 1 family member 3 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101711233, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Mta3
    Gene description
    metastasis associated 1 family member 3
    See related
    Ensembl:ENSHGLG00000013809
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624738.1 (24247752..24403234)

    NW_004624738.1Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel modifier subfamily G member 3 Neighboring gene 60S ribosomal protein L21-like Neighboring gene uncharacterized LOC110347958 Neighboring gene 3-hydroxyanthranilate 3,4-dioxygenase Neighboring gene transfer RNA isoleucine (anticodon UAU)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624738 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FRAMA: from RNA-seq data to annotated mRNA assemblies. Bens M, et al. BMC Genomics, 2016 Jan 14. PMID 26763976, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NuRD complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metastasis-associated protein MTA3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310263.1 → NP_001297192.1  metastasis-associated protein MTA3

      See identical proteins and their annotated locations for NP_001297192.1

      Status: PROVISIONAL

      Source sequence(s)
      KM486739
      UniProtKB/TrEMBL
      A0A0A7HV71
      Related
      ENSHGLP00000019253.1, ENSHGLT00000019444.1
      Conserved Domains (6) summary
      smart00717
      Location:269 → 316
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:270 → 315
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      smart00401
      Location:376 → 425
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      cd00202
      Location:378 → 426
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
      cd04709
      Location:3 → 170
      BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
      pfam01448
      Location:150 → 201
      ELM2; ELM2 domain

    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624738.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      24247752..24403234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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