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    Eefsec eukaryotic elongation factor, selenocysteine-tRNA specific [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101705575, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Eefsec
    Gene description
    eukaryotic elongation factor, selenocysteine-tRNA specific
    Locus tag
    GW7_10953
    See related
    Ensembl:ENSHGLG00000000094
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624961.1 (195904..414552, complement)

    NW_004624961.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106008681 Neighboring gene DnaJ heat shock protein family (Hsp40) member B8 Neighboring gene RuvB like AAA ATPase 1 Neighboring gene SEC61 translocon subunit alpha 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624961 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in selenocysteine incorporation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    selenocysteine-specific elongation factor
    Names
    Selenocysteine-specific elongation factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624961.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      195904..414552 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013069442.2 → XP_012924896.1  selenocysteine-specific elongation factor isoform X2

      Related
      ENSHGLP00000000067.1, ENSHGLT00000000095.1
      Conserved Domains (4) summary
      cd01889
      Location:8 → 196
      SelB_euk; SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome
      pfam00009
      Location:8 → 194
      GTP_EFTU; Elongation factor Tu GTP binding domain
      cd03696
      Location:209 → 291
      SelB_II; Domain II of elongation factor SelB
      cd04094
      Location:296 → 435
      eSelB_III; Domain III of eukaryotic and archaeal elongation factor SelB

    2. XM_013069440.2 → XP_012924894.1  selenocysteine-specific elongation factor isoform X1

      Conserved Domains (4) summary
      cd01889
      Location:8 → 196
      SelB_euk; SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome
      pfam00009
      Location:8 → 194
      GTP_EFTU; Elongation factor Tu GTP binding domain
      cd03696
      Location:209 → 291
      SelB_II; Domain II of elongation factor SelB
      cd04094
      Location:296 → 435
      eSelB_III; Domain III of eukaryotic and archaeal elongation factor SelB

    3. XM_021252437.1 → XP_021108096.1  selenocysteine-specific elongation factor isoform X4

      Conserved Domains (3) summary
      cd03696
      Location:112 → 194
      SelB_II; Domain II of elongation factor SelB
      cd04094
      Location:199 → 338
      eSelB_III; Domain III of eukaryotic and archaeal elongation factor SelB
      cl21455
      Location:1 → 99
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_004875147.3 → XP_004875204.2  selenocysteine-specific elongation factor isoform X4

      See identical proteins and their annotated locations for XP_004875204.2

      Conserved Domains (3) summary
      cd03696
      Location:112 → 194
      SelB_II; Domain II of elongation factor SelB
      cd04094
      Location:199 → 338
      eSelB_III; Domain III of eukaryotic and archaeal elongation factor SelB
      cl21455
      Location:1 → 99
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. XM_004875148.2 → XP_004875205.2  selenocysteine-specific elongation factor isoform X4

      See identical proteins and their annotated locations for XP_004875205.2

      Conserved Domains (3) summary
      cd03696
      Location:112 → 194
      SelB_II; Domain II of elongation factor SelB
      cd04094
      Location:199 → 338
      eSelB_III; Domain III of eukaryotic and archaeal elongation factor SelB
      cl21455
      Location:1 → 99
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. XM_004875146.2 → XP_004875203.1  selenocysteine-specific elongation factor isoform X3

      See identical proteins and their annotated locations for XP_004875203.1

      UniProtKB/TrEMBL
      G5BII3
      Related
      ENSHGLP00000000068.1, ENSHGLT00000000096.1
      Conserved Domains (4) summary
      cd01889
      Location:8 → 196
      SelB_euk; SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome
      pfam00009
      Location:8 → 194
      GTP_EFTU; Elongation factor Tu GTP binding domain
      cd03696
      Location:209 → 291
      SelB_II; Domain II of elongation factor SelB
      cd04094
      Location:296 → 435
      eSelB_III; Domain III of eukaryotic and archaeal elongation factor SelB
    Nucleotide Protein
    Heading Accession and Version

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