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    Xpnpep1 X-prolyl aminopeptidase 1 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101698797, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Xpnpep1
    Gene description
    X-prolyl aminopeptidase 1
    See related
    Ensembl:ENSHGLG00000013820
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624737.1 (36343159..36402940)

    NW_004624737.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110347838 Neighboring gene adducin 3 Neighboring gene tubulin beta-7 chain pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624737 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    xaa-Pro aminopeptidase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624737.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      36343159..36402940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021253465.1 → XP_021109124.1  xaa-Pro aminopeptidase 1 isoform X5

      UniProtKB/TrEMBL
      A0A0P6J1I6
      Conserved Domains (4) summary
      cd01085
      Location:372 → 594
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:600 → 625
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:200 → 369
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
      cl23800
      Location:53 → 197
      Creatinase_N; Creatinase/Prolidase N-terminal domain

    2. XM_021253460.1 → XP_021109119.1  xaa-Pro aminopeptidase 1 isoform X1

      UniProtKB/TrEMBL
      A0A0P6J1I6
      Conserved Domains (4) summary
      cd01085
      Location:380 → 602
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:608 → 670
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:208 → 377
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
      cl23800
      Location:53 → 205
      Creatinase_N; Creatinase/Prolidase N-terminal domain

    3. XM_004838960.3 → XP_004839017.1  xaa-Pro aminopeptidase 1 isoform X2

      UniProtKB/TrEMBL
      A0A0P6J1I6
      Related
      ENSHGLP00000019275.1, ENSHGLT00000019466.1
      Conserved Domains (5) summary
      COG0006
      Location:238 → 609
      PepP; Xaa-Pro aminopeptidase [Amino acid transport and metabolism]
      cd01085
      Location:372 → 594
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:600 → 662
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:207 → 369
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
      cl23800
      Location:53 → 197
      Creatinase_N; Creatinase/Prolidase N-terminal domain

    4. XM_021253464.1 → XP_021109123.1  xaa-Pro aminopeptidase 1 isoform X4

      UniProtKB/TrEMBL
      G5BKB6
      Conserved Domains (4) summary
      cd01085
      Location:329 → 551
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:557 → 619
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:157 → 326
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
      cl23800
      Location:10 → 154
      Creatinase_N; Creatinase/Prolidase N-terminal domain

    5. XM_021253463.1 → XP_021109122.1  xaa-Pro aminopeptidase 1 isoform X3

      UniProtKB/TrEMBL
      G5BKB6
      Conserved Domains (4) summary
      cd01085
      Location:337 → 559
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:565 → 627
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:165 → 334
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
      cl23800
      Location:10 → 162
      Creatinase_N; Creatinase/Prolidase N-terminal domain

    6. XM_021253462.1 → XP_021109121.1  xaa-Pro aminopeptidase 1 isoform X3

      UniProtKB/TrEMBL
      G5BKB6
      Conserved Domains (4) summary
      cd01085
      Location:337 → 559
      APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
      pfam16188
      Location:565 → 627
      Peptidase_M24_C; C-terminal region of peptidase_M24
      pfam16189
      Location:165 → 334
      Creatinase_N_2; Creatinase/Prolidase N-terminal domain
      cl23800
      Location:10 → 162
      Creatinase_N; Creatinase/Prolidase N-terminal domain
    Nucleotide Protein
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