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    Nkx2-2 NK2 homeobox 2 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101697794, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Nkx2-2
    Gene description
    NK2 homeobox 2
    Locus tag
    GW7_00710
    See related
    Ensembl:ENSHGLG00000012498
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624741.1 (21857911..21860128, complement)

    NW_004624741.1Genomic Context describing neighboring genes Neighboring gene 5'-3' exoribonuclease 2 Neighboring gene NK2 homeobox 4 Neighboring gene paired box 1 Neighboring gene uncharacterized LOC110348286

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624741 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein Nkx-2.2
    Names
    Homeobox protein Nkx-2.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624741.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      21857911..21860128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004840902.2 → XP_004840959.1  homeobox protein Nkx-2.2

      See identical proteins and their annotated locations for XP_004840959.1

      UniProtKB/TrEMBL
      G5CBC3
      Related
      ENSHGLP00000017449.1, ENSHGLT00000017623.1
      Conserved Domains (2) summary
      COG5576
      Location:96 → 217
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:131 → 184
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version

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