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    Irak2 interleukin 1 receptor associated kinase 2 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101697284, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Irak2
    Gene description
    interleukin 1 receptor associated kinase 2
    See related
    Ensembl:ENSHGLG00000014561
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624731.1 (5294464..5348426, complement)

    NW_004624731.1Genomic Context describing neighboring genes Neighboring gene ghrelin and obestatin prepropeptide Neighboring gene TatD DNase domain containing 2 Neighboring gene matrin-3 pseudogene Neighboring gene von Hippel-Lindau tumor suppressor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624731 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interleukin-1-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-1 receptor-associated kinase-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624731.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      5294464..5348426 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021260676.1 → XP_021116335.1  interleukin-1 receptor-associated kinase-like 2 isoform X5

      Conserved Domains (2) summary
      cd08795
      Location:4 → 91
      Death_IRAK2; Death domain of Interleukin 1 Receptor Associated Kinase-2
      cl21453
      Location:178 → 433
      PKc_like; Protein Kinases, catalytic domain

    2. XM_004835793.2 → XP_004835850.1  interleukin-1 receptor-associated kinase-like 2 isoform X1

      Related
      ENSHGLP00000020369.1, ENSHGLT00000020571.1
      Conserved Domains (2) summary
      cd08795
      Location:4 → 91
      Death_IRAK2; Death domain of Interleukin 1 Receptor Associated Kinase-2
      cl21453
      Location:216 → 498
      PKc_like; Protein Kinases, catalytic domain

    3. XM_021260674.1 → XP_021116333.1  interleukin-1 receptor-associated kinase-like 2 isoform X4

      Conserved Domains (2) summary
      cl14633
      Location:4 → 35
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl21453
      Location:155 → 437
      PKc_like; Protein Kinases, catalytic domain

    4. XM_021260660.1 → XP_021116319.1  interleukin-1 receptor-associated kinase-like 2 isoform X2

      Conserved Domains (2) summary
      cl14633
      Location:2 → 62
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl21453
      Location:187 → 469
      PKc_like; Protein Kinases, catalytic domain

    5. XM_021260670.1 → XP_021116329.1  interleukin-1 receptor-associated kinase-like 2 isoform X3

      Conserved Domains (2) summary
      cl14633
      Location:1 → 44
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl21453
      Location:169 → 451
      PKc_like; Protein Kinases, catalytic domain

    6. XM_021260655.1 → XP_021116314.1  interleukin-1 receptor-associated kinase-like 2 isoform X2

      Conserved Domains (2) summary
      cl14633
      Location:2 → 62
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl21453
      Location:187 → 469
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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