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    Isg20 interferon stimulated exonuclease gene 20 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101696638, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Isg20
    Gene description
    interferon stimulated exonuclease gene 20
    Locus tag
    GW7_08808
    See related
    Ensembl:ENSHGLG00000009077
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624768.1 (15949591..15958816)

    NW_004624768.1Genomic Context describing neighboring genes Neighboring gene DET1 partner of COP1 E3 ubiquitin ligase Neighboring gene uncharacterized LOC110350745 Neighboring gene apoptosis enhancing nuclease Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene uncharacterized LOC110350746 Neighboring gene aggrecan

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624768 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in RNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of viral genome replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon-stimulated gene 20 kDa protein
    Names
    Interferon-stimulated gene 20 kDa protein
    interferon-stimulated 20 kDa protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624768.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      15949591..15958816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004852746.3 → XP_004852803.1  interferon-stimulated gene 20 kDa protein

      UniProtKB/TrEMBL
      G5CA83
      Conserved Domains (1) summary
      cl10012
      Location:8 → 163
      DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily

    2. XM_021264803.1 → XP_021120462.1  interferon-stimulated gene 20 kDa protein

      UniProtKB/TrEMBL
      G5CA83
      Related
      ENSHGLP00000012693.1, ENSHGLT00000012830.1
      Conserved Domains (1) summary
      cl10012
      Location:8 → 163
      DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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