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    DENND5A DENN domain containing 5A [ Ovis aries (sheep) ]

    Gene ID: 101123580, updated on 8-Mar-2024

    Summary

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    Gene symbol
    DENND5A
    Gene description
    DENN domain containing 5A
    See related
    EnsemblRapid:ENSOARG00020018228
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 15
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 15 NC_056068.1 (43068417..43170104)

    Chromosome 15 - NC_056068.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 41B Neighboring gene NFATC2-interacting protein-like Neighboring gene G2/mitotic-specific cyclin-B1-like Neighboring gene signal peptide, CUB domain and EGF like domain containing 2 Neighboring gene small nucleolar RNA U3 Neighboring gene nuclear receptor interacting protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056068.1 Chromosome 15 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DENN domain-containing protein 5A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056068.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      43068417..43170104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015101040.4 → XP_014956526.2  DENN domain-containing protein 5A isoform X1

      UniProtKB/TrEMBL
      A0A6P3YMZ1
      Related
      ENSOARP00020045649.1, ENSOART00020050662.1
      Conserved Domains (5) summary
      smart00801
      Location:517 → 592
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:16 → 142
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      cd01757
      Location:958 → 1066
      PLAT_RAB6IP1; PLAT/LH2 domain present in RAB6 interacting protein 1 (Rab6IP1)_like family. PLAT/LH2 domains consists of an eight stranded beta-barrel. In RabIP1 this domain may participate in lipid-mediated modulation of Rab6IP1's function via it's generally proposed ...
      pfam02141
      Location:206 → 394
      DENN; DENN (AEX-3) domain
      cl02689
      Location:799 → 946
      RUN; RUN domain

    2. XM_060399925.1 → XP_060255908.1  DENN domain-containing protein 5A isoform X2

      UniProtKB/TrEMBL
      W5PU82
    Nucleotide Protein Strain
    Heading Accession and Version

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