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    MPO myeloperoxidase [ Ovis aries (sheep) ]

    Gene ID: 101123053, updated on 8-Mar-2024

    Summary

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    Gene symbol
    MPO
    Gene description
    myeloperoxidase
    See related
    EnsemblRapid:ENSOARG00020020290
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See MPO in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 11 NC_056064.1 (8940092..8950720, complement)

    Chromosome 11 - NC_056064.1Genomic Context describing neighboring genes Neighboring gene MKS transition zone complex subunit 1 Neighboring gene U6 spliceosomal RNA Neighboring gene lactoperoxidase Neighboring gene uncharacterized LOC132657322 Neighboring gene TSPO associated protein 1 Neighboring gene SPT4 homolog, DSIF elongation factor subunit Neighboring gene ring finger protein 43

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056064.1 Chromosome 11 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Presence of melatonin-catabolizing non-specific enzymes myeloperoxidase and indoleamine 2,3-dioxygenase in the ram reproductive tract. Martínez-Marcos P, et al. Reprod Domest Anim, 2019 Dec. PMID 31587393

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Melatonin-catabolizing enzymes MPO, IDO1 and IDO2 are expressed in the ram reproductive tract, and MPO is the most expressed one, mainly in the testis and the bulbourethral glands.
      Title: Presence of melatonin-catabolizing non-specific enzymes myeloperoxidase and indoleamine 2,3-dioxygenase in the ram reproductive tract.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myeloperoxidase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056064.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      8940092..8950720 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027975362.2 → XP_027831163.1  myeloperoxidase

      UniProtKB/TrEMBL
      W5PHQ0
      Conserved Domains (1) summary
      cd09824
      Location:289 → 702
      myeloperoxidase_like; Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases

    2. XM_042255270.1 → XP_042111204.1  myeloperoxidase

      UniProtKB/TrEMBL
      W5PHQ0
      Related
      ENSOARP00020058584.1, ENSOART00020078801.1
      Conserved Domains (1) summary
      cd09824
      Location:289 → 702
      myeloperoxidase_like; Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases
    Nucleotide Protein Strain
    Heading Accession and Version

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