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    OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [ Ovis aries (sheep) ]

    Gene ID: 101121853, updated on 3-Apr-2024

    Summary

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    Gene symbol
    OBSCN
    Gene description
    obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
    See related
    EnsemblRapid:ENSOARG00020017214
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See OBSCN in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    123
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 5 NC_056058.1 (2440700..2672300, complement)

    Chromosome 5 - NC_056058.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114114812 Neighboring gene tripartite motif containing 17 Neighboring gene tripartite motif containing 11 Neighboring gene mannose-P-dolichol utilization defect 1 protein-like Neighboring gene iron-sulfur cluster assembly factor IBA57 Neighboring gene uncharacterized LOC132659858

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056058.1 Chromosome 5 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    obscurin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056058.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      2440700..2672300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042249479.1 → XP_042105413.1  obscurin isoform X13

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:734 → 782
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6903 → 6965
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8842 → 8920
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6433 → 6516
      IG_like; Immunoglobulin like
      PHA03247
      Location:8253 → 8677
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5830 → 5915
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7183 → 7307
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6443 → 6447
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6998 → 7174
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7769 → 8025
      PKc_like; Protein Kinases, catalytic domain

    2. XM_060416153.1 → XP_060272136.1  obscurin isoform X17

    3. XM_042249500.1 → XP_042105434.1  obscurin isoform X29

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6719 → 6781
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8658 → 8736
      FN3; Fibronectin type 3 domain
      smart00409
      Location:7141 → 7223
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:8069 → 8493
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5646 → 5731
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6999 → 7123
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6814 → 6990
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7585 → 7841
      PKc_like; Protein Kinases, catalytic domain

    4. XM_060416154.1 → XP_060272137.1  obscurin isoform X25

    5. XM_042249480.1 → XP_042105414.1  obscurin isoform X16

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6903 → 6965
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8842 → 8920
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6433 → 6516
      IG_like; Immunoglobulin like
      PHA03247
      Location:8253 → 8677
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5830 → 5915
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7183 → 7307
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6443 → 6447
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6998 → 7174
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7769 → 8025
      PKc_like; Protein Kinases, catalytic domain

    6. XM_042249506.1 → XP_042105440.1  obscurin isoform X34

      UniProtKB/TrEMBL
      A0A836D2J6
      Related
      ENSOARP00020047794.1, ENSOART00020027910.2
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6627 → 6689
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8566 → 8644
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:116 → 201
      IG_like; Immunoglobulin like
      PHA03247
      Location:7977 → 8401
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5554 → 5639
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6907 → 7031
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:127 → 131
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6722 → 6898
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7493 → 7749
      PKc_like; Protein Kinases, catalytic domain

    7. XM_042249476.1 → XP_042105410.1  obscurin isoform X14

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6903 → 6965
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8842 → 8920
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6433 → 6516
      IG_like; Immunoglobulin like
      PHA03247
      Location:8253 → 8677
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5830 → 5915
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7183 → 7307
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6443 → 6447
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6998 → 7174
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7769 → 8025
      PKc_like; Protein Kinases, catalytic domain

    8. XM_042249482.1 → XP_042105416.1  obscurin isoform X18

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6903 → 6965
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8842 → 8920
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6433 → 6516
      IG_like; Immunoglobulin like
      PHA03247
      Location:8253 → 8677
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5830 → 5915
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7183 → 7307
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6443 → 6447
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6998 → 7174
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7769 → 8025
      PKc_like; Protein Kinases, catalytic domain

    9. XM_042249481.1 → XP_042105415.1  obscurin isoform X15

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6903 → 6965
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8842 → 8920
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6433 → 6516
      IG_like; Immunoglobulin like
      PHA03247
      Location:8253 → 8677
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5830 → 5915
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7183 → 7307
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6443 → 6447
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6998 → 7174
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7769 → 8025
      PKc_like; Protein Kinases, catalytic domain

    10. XM_042249478.1 → XP_042105412.1  obscurin isoform X12

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6903 → 6965
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8842 → 8920
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6433 → 6516
      IG_like; Immunoglobulin like
      PHA03247
      Location:8253 → 8677
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5830 → 5915
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7183 → 7307
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6443 → 6447
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6998 → 7174
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7769 → 8025
      PKc_like; Protein Kinases, catalytic domain

    11. XM_042249475.1 → XP_042105409.1  obscurin isoform X11

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    12. XM_042249504.1 → XP_042105438.1  obscurin isoform X32

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6643 → 6705
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8582 → 8660
      FN3; Fibronectin type 3 domain
      smart00409
      Location:6173 → 6256
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:7993 → 8417
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5570 → 5655
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6923 → 7047
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6738 → 6914
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7509 → 7765
      PKc_like; Protein Kinases, catalytic domain

    13. XM_060416159.1 → XP_060272142.1  obscurin isoform X38

    14. XM_060416155.1 → XP_060272138.1  obscurin isoform X27

    15. XM_060416158.1 → XP_060272141.1  obscurin isoform X37

    16. XM_060416157.1 → XP_060272140.1  obscurin isoform X36

    17. XM_060416156.1 → XP_060272139.1  obscurin isoform X28

    18. XM_042249490.1 → XP_042105424.1  obscurin isoform X23

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6819 → 6881
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8758 → 8836
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:3000 → 3069
      IG_like; Immunoglobulin like
      PHA03247
      Location:8169 → 8593
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5746 → 5831
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7099 → 7223
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:8681 → 8685
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6914 → 7090
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7685 → 7941
      PKc_like; Protein Kinases, catalytic domain

    19. XM_042249465.1 → XP_042105399.1  obscurin isoform X10

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    20. XM_042249498.1 → XP_042105432.1  obscurin isoform X26

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6731 → 6793
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8670 → 8748
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:116 → 201
      IG_like; Immunoglobulin like
      PHA03247
      Location:8081 → 8505
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5658 → 5743
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7011 → 7135
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:127 → 131
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6826 → 7002
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7597 → 7853
      PKc_like; Protein Kinases, catalytic domain

    21. XM_042249488.1 → XP_042105422.1  obscurin isoform X22

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6819 → 6881
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8758 → 8836
      FN3; Fibronectin type 3 domain
      smart00409
      Location:7582 → 7664
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:8169 → 8593
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5746 → 5831
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7099 → 7223
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6914 → 7090
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7685 → 7941
      PKc_like; Protein Kinases, catalytic domain

    22. XM_042249466.1 → XP_042105400.1  obscurin isoform X6

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    23. XM_042249511.1 → XP_042105445.1  obscurin isoform X35

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6467 → 6529
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8406 → 8484
      FN3; Fibronectin type 3 domain
      smart00409
      Location:5997 → 6080
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:7817 → 8241
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5394 → 5479
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6747 → 6871
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6562 → 6738
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7333 → 7589
      PKc_like; Protein Kinases, catalytic domain

    24. XM_042249487.1 → XP_042105421.1  obscurin isoform X21

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6819 → 6881
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8758 → 8836
      FN3; Fibronectin type 3 domain
      smart00409
      Location:116 → 201
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:8169 → 8593
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5746 → 5831
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7099 → 7223
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6914 → 7090
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7685 → 7941
      PKc_like; Protein Kinases, catalytic domain

    25. XM_042249505.1 → XP_042105439.1  obscurin isoform X33

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6639 → 6701
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8578 → 8656
      FN3; Fibronectin type 3 domain
      smart00409
      Location:247 → 327
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:7989 → 8413
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5566 → 5651
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6919 → 7043
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6734 → 6910
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7505 → 7761
      PKc_like; Protein Kinases, catalytic domain

    26. XM_042249486.1 → XP_042105420.1  obscurin isoform X19

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6819 → 6881
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8758 → 8836
      FN3; Fibronectin type 3 domain
      smart00409
      Location:6349 → 6432
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:8169 → 8593
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5746 → 5831
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7099 → 7223
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6914 → 7090
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7685 → 7941
      PKc_like; Protein Kinases, catalytic domain

    27. XM_042249469.1 → XP_042105403.1  obscurin isoform X8

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    28. XM_042249468.1 → XP_042105402.1  obscurin isoform X7

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    29. XM_042249502.1 → XP_042105436.1  obscurin isoform X31

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6643 → 6705
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8582 → 8660
      FN3; Fibronectin type 3 domain
      smart00409
      Location:6173 → 6256
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:7993 → 8417
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5570 → 5655
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6923 → 7047
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6738 → 6914
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7509 → 7765
      PKc_like; Protein Kinases, catalytic domain

    30. XM_042249471.1 → XP_042105405.1  obscurin isoform X9

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    31. XM_042249503.1 → XP_042105437.1  obscurin isoform X30

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6643 → 6705
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8582 → 8660
      FN3; Fibronectin type 3 domain
      smart00409
      Location:6173 → 6256
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03247
      Location:7993 → 8417
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5570 → 5655
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:6923 → 7047
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6738 → 6914
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7509 → 7765
      PKc_like; Protein Kinases, catalytic domain

    32. XM_042249493.1 → XP_042105427.1  obscurin isoform X20

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6819 → 6881
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8758 → 8836
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:7241 → 7323
      IG_like; Immunoglobulin like
      PHA03247
      Location:8169 → 8593
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5746 → 5831
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7099 → 7223
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:7248 → 7252
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6914 → 7090
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7685 → 7941
      PKc_like; Protein Kinases, catalytic domain

    33. XM_042249467.1 → XP_042105401.1  obscurin isoform X4

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    34. XM_042249473.1 → XP_042105407.1  obscurin isoform X5

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6907 → 6969
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8846 → 8924
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6437 → 6520
      IG_like; Immunoglobulin like
      PHA03247
      Location:8257 → 8681
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5834 → 5919
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7187 → 7311
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6447 → 6451
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7002 → 7178
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7773 → 8029
      PKc_like; Protein Kinases, catalytic domain

    35. XM_042249495.1 → XP_042105429.1  obscurin isoform X24

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6815 → 6877
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8754 → 8832
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6345 → 6428
      IG_like; Immunoglobulin like
      PHA03247
      Location:8165 → 8589
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5742 → 5827
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7095 → 7219
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6355 → 6359
      Ig; Ig strand B [structural motif]
      cl02571
      Location:6910 → 7086
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7681 → 7937
      PKc_like; Protein Kinases, catalytic domain

    36. XM_042249462.1 → XP_042105396.1  obscurin isoform X2

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6994 → 7056
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8933 → 9011
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6524 → 6607
      IG_like; Immunoglobulin like
      PHA03247
      Location:8344 → 8768
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5922 → 6007
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7274 → 7398
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6534 → 6538
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7089 → 7265
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7860 → 8116
      PKc_like; Protein Kinases, catalytic domain

    37. XM_042249464.1 → XP_042105398.1  obscurin isoform X3

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6995 → 7057
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8926 → 9004
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:7417 → 7499
      IG_like; Immunoglobulin like
      PHA03247
      Location:8337 → 8761
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5922 → 6007
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7275 → 7399
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:7424 → 7428
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7090 → 7266
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7853 → 8109
      PKc_like; Protein Kinases, catalytic domain

    38. XM_042249460.1 → XP_042105394.1  obscurin isoform X1

      UniProtKB/TrEMBL
      A0A836D2J6
      Conserved Domains (11) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6995 → 7057
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00060
      Location:8934 → 9012
      FN3; Fibronectin type 3 domain
      smart00409
      Location:20 → 99
      IG; Immunoglobulin
      smart00410
      Location:6525 → 6608
      IG_like; Immunoglobulin like
      PHA03247
      Location:8345 → 8769
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:5922 → 6007
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7275 → 7399
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:6535 → 6539
      Ig; Ig strand B [structural motif]
      cl02571
      Location:7090 → 7266
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl21453
      Location:7861 → 8117
      PKc_like; Protein Kinases, catalytic domain

    39. XM_060416162.1 → XP_060272145.1  obscurin isoform X42

    40. XM_042249514.1 → XP_042105448.1  obscurin isoform X41

      UniProtKB/TrEMBL
      W5P620
      Conserved Domains (9) summary
      smart00408
      Location:905 → 968
      IGc2; Immunoglobulin C-2 Type
      cd12025
      Location:6815 → 6877
      SH3_Obscurin_like; Src homology 3 domain of Obscurin and similar proteins
      smart00409
      Location:6345 → 6428
      IG; Immunoglobulin
      smart00410
      Location:20 → 99
      IG_like; Immunoglobulin like
      PHA03307
      Location:5717 → 6074
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:5742 → 5827
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd13239
      Location:7095 → 7219
      PH_Obscurin; Obscurin pleckstrin homology (PH) domain
      cd00096
      Location:40 → 44
      Ig; Ig strand C [structural motif]
      cl02571
      Location:6910 → 7086
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    41. XM_060416161.1 → XP_060272144.1  obscurin isoform X40

    42. XM_060416160.1 → XP_060272143.1  obscurin isoform X39

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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