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    EPN2 epsin 2 [ Ovis aries (sheep) ]

    Gene ID: 101119060, updated on 8-Mar-2024

    Summary

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    Gene symbol
    EPN2
    Gene description
    epsin 2
    See related
    EnsemblRapid:ENSOARG00020026384
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 11 NC_056064.1 (33870483..33922739, complement)

    Chromosome 11 - NC_056064.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121820592 Neighboring gene B9 domain containing 1 Neighboring gene GRB2 related adaptor protein Neighboring gene solute carrier family 5 member 10 Neighboring gene family with sequence similarity 83 member G

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056064.1 Chromosome 11 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables clathrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of clathrin vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    epsin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056064.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      33870483..33922739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027974817.2 → XP_027830618.1  epsin-2 isoform X4

      UniProtKB/TrEMBL
      W5QAF3
      Related
      ENSOARP00020034480.2, ENSOART00020041522.2

    2. XM_027974815.2 → XP_027830616.1  epsin-2 isoform X2

      UniProtKB/TrEMBL
      W5QAF3

    3. XM_027974816.2 → XP_027830617.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A6P7EHA0, W5QAF3, W5QAF4
      Conserved Domains (2) summary
      PHA03247
      Location:255 → 564
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    4. XM_027974814.2 → XP_027830615.1  epsin-2 isoform X1

      UniProtKB/TrEMBL
      W5QAF3

    5. XM_042255726.2 → XP_042111660.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A6P7EHA0, W5QAF3, W5QAF4
      Conserved Domains (2) summary
      PHA03247
      Location:255 → 564
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    6. XM_012185795.5 → XP_012041185.1  epsin-2 isoform X1

      See identical proteins and their annotated locations for XP_012041185.1

      UniProtKB/TrEMBL
      W5QAF3
      Conserved Domains (1) summary
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...

    7. XM_042255727.2 → XP_042111661.1  epsin-2 isoform X3

      UniProtKB/TrEMBL
      A0A6P7EHA0, W5QAF3, W5QAF4
      Conserved Domains (2) summary
      PHA03247
      Location:255 → 564
      PHA03247; large tegument protein UL36; Provisional
      cd16990
      Location:19 → 141
      ENTH_Epsin; Epsin N-Terminal Homology (ENTH) domain of Epsin family

    8. XM_012185794.5 → XP_012041184.1  epsin-2 isoform X1

      See identical proteins and their annotated locations for XP_012041184.1

      UniProtKB/TrEMBL
      W5QAF3
      Related
      ENSOARP00020059124.1, ENSOART00020067014.1
      Conserved Domains (1) summary
      cd03571
      Location:19 → 141
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
    Nucleotide Protein Strain
    Heading Accession and Version

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