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    FLT4 fms related receptor tyrosine kinase 4 [ Ovis aries (sheep) ]

    Gene ID: 101117247, updated on 11-Apr-2024

    Summary

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    Gene symbol
    FLT4
    Gene description
    fms related receptor tyrosine kinase 4
    See related
    EnsemblRapid:ENSOARG00020009822
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 5 NC_056058.1 (346023..387809)

    Chromosome 5 - NC_056058.1Genomic Context describing neighboring genes Neighboring gene nuclear envelope pore membrane protein POM 121-like Neighboring gene 5S ribosomal RNA Neighboring gene small integral membrane protein 30-like Neighboring gene CCR4-NOT transcription complex subunit 6 Neighboring gene BAG family molecular chaperone regulator 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056058.1 Chromosome 5 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vascular endothelial growth factor receptor 3
    Names
    fms related tyrosine kinase 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056058.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      346023..387809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_060416107.1 → XP_060272090.1  vascular endothelial growth factor receptor 3 isoform X3

      Related
      ENSOARP00020036023.1, ENSOART00020074649.1

    2. XM_042249454.1 → XP_042105388.1  vascular endothelial growth factor receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A836D4W8
      Conserved Domains (6) summary
      smart00408
      Location:697 → 759
      IGc2; Immunoglobulin C-2 Type
      smart00409
      Location:568 → 661
      IG; Immunoglobulin
      smart00410
      Location:241 → 330
      IG_like; Immunoglobulin like
      pfam17988
      Location:774 → 807
      VEGFR-2_TMD; VEGFR-2 Transmembrane domain
      cd00096
      Location:699 → 703
      Ig; Ig strand B [structural motif]
      cl21453
      Location:841 → 1180
      PKc_like; Protein Kinases, catalytic domain

    3. XM_027969266.2 → XP_027825067.2  vascular endothelial growth factor receptor 3 isoform X2

      UniProtKB/TrEMBL
      A0A836D4W8
      Related
      ENSOARP00020013080.2, ENSOART00020015813.2
      Conserved Domains (6) summary
      smart00408
      Location:696 → 758
      IGc2; Immunoglobulin C-2 Type
      smart00409
      Location:567 → 660
      IG; Immunoglobulin
      smart00410
      Location:241 → 330
      IG_like; Immunoglobulin like
      pfam17988
      Location:773 → 806
      VEGFR-2_TMD; VEGFR-2 Transmembrane domain
      cd00096
      Location:698 → 702
      Ig; Ig strand B [structural motif]
      cl21453
      Location:840 → 1179
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

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