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    KHK ketohexokinase [ Ovis aries (sheep) ]

    Gene ID: 101113479, updated on 8-Mar-2024

    Summary

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    Gene symbol
    KHK
    Gene description
    ketohexokinase
    See related
    EnsemblRapid:ENSOARG00020001333
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (34169705..34186473)

    Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene AGBL carboxypeptidase 5 Neighboring gene oligosaccharyltransferase complex subunit 4, non-catalytic Neighboring gene elastin microfibril interfacer 1 Neighboring gene uncharacterized LOC114113902 Neighboring gene prolactin regulatory element binding Neighboring gene abhydrolase domain containing 1 Neighboring gene proline rich 30

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ketohexokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fructose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ketohexokinase
    Names
    ketohexokinase (fructokinase)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      34169705..34186473
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042245901.1 → XP_042101835.1  ketohexokinase isoform X4

      Conserved Domains (1) summary
      cd01939
      Location:5 → 350
      Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

    2. XM_060411967.1 → XP_060267950.1  ketohexokinase isoform X8

    3. XM_027966606.2 → XP_027822407.1  ketohexokinase isoform X11

    4. XM_027966608.2 → XP_027822409.1  ketohexokinase isoform X15

    5. XM_060411963.1 → XP_060267946.1  ketohexokinase isoform X1

    6. XM_042245900.1 → XP_042101834.1  ketohexokinase isoform X2

      Conserved Domains (1) summary
      cd01939
      Location:5 → 367
      Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

    7. XM_060411964.1 → XP_060267947.1  ketohexokinase isoform X3

    8. XM_042245902.1 → XP_042101836.1  ketohexokinase isoform X7

      UniProtKB/TrEMBL
      W5QCS8
      Related
      ENSOARP00020001669.2, ENSOART00020002003.2
      Conserved Domains (1) summary
      cd01939
      Location:5 → 340
      Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

    9. XM_060411966.1 → XP_060267949.1  ketohexokinase isoform X6

    10. XM_060411968.1 → XP_060267951.1  ketohexokinase isoform X10

      Related
      ENSOARP00020040686.1, ENSOART00020066987.1

    11. XM_004005749.5 → XP_004005798.1  ketohexokinase isoform X14

      See identical proteins and their annotated locations for XP_004005798.1

      Related
      ENSOARP00020058561.1, ENSOART00020042435.1
      Conserved Domains (1) summary
      cd01939
      Location:5 → 295
      Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

    12. XM_060411965.1 → XP_060267948.1  ketohexokinase isoform X5

    13. XM_027966605.2 → XP_027822406.1  ketohexokinase isoform X9

    14. XM_004005748.5 → XP_004005797.1  ketohexokinase isoform X13

      See identical proteins and their annotated locations for XP_004005797.1

      UniProtKB/TrEMBL
      A0A6P3E9S5
      Related
      ENSOARP00020001666.1, ENSOART00020002000.2
      Conserved Domains (1) summary
      cd01939
      Location:5 → 295
      Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

    15. XM_060411969.1 → XP_060267952.1  ketohexokinase isoform X12

    16. XM_027966610.2 → XP_027822411.1  ketohexokinase isoform X16

    Nucleotide Protein Strain
    Heading Accession and Version

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