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    VPS18 VPS18 core subunit of CORVET and HOPS complexes [ Ovis aries (sheep) ]

    Gene ID: 101111552, updated on 8-Mar-2024

    Summary

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    Gene symbol
    VPS18
    Gene description
    VPS18 core subunit of CORVET and HOPS complexes
    See related
    EnsemblRapid:ENSOARG00020013603
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See VPS18 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 7 NC_056060.1 (34633481..34642224)

    Chromosome 7 - NC_056060.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14D Neighboring gene serine peptidase inhibitor, Kunitz type 1 Neighboring gene ras homolog family member V Neighboring gene uncharacterized LOC132660127 Neighboring gene delta like canonical Notch ligand 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056060.1 Chromosome 7 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosome to lysosome transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lysosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in organelle fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle docking involved in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of HOPS complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vacuolar protein sorting-associated protein 18 homolog
    Names
    VPS18, CORVET/HOPS core subunit
    vacuolar protein sorting 18 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056060.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      34633481..34642224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004010456.6 → XP_004010505.3  vacuolar protein sorting-associated protein 18 homolog

      UniProtKB/TrEMBL
      A0A6P3E7L8
      Related
      ENSOARP00020017216.1, ENSOART00020020799.2
      Conserved Domains (3) summary
      cd16689
      Location:851 → 881
      RING-H2_Vps18; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 18 (Vps18) and similar proteins
      pfam00637
      Location:615 → 743
      Clathrin; Region in Clathrin and VPS
      pfam05131
      Location:291 → 434
      Pep3_Vps18; Pep3/Vps18/deep orange family
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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