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    LHX3 LIM homeobox 3 [ Ovis aries (sheep) ]

    Gene ID: 101111265, updated on 8-Mar-2024

    Summary

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    Gene symbol
    LHX3
    Gene description
    LIM homeobox 3
    See related
    EnsemblRapid:ENSOARG00020004662
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (3244811..3253332)

    Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 187 Neighboring gene quiescin sulfhydryl oxidase 2 Neighboring gene uncharacterized LOC105607253 Neighboring gene transmembrane protein 250 Neighboring gene NACC family member 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LIM/homeobox protein Lhx3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      3244811..3253332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027966195.3 → XP_027821996.2  LIM/homeobox protein Lhx3 isoform X2

      UniProtKB/TrEMBL
      W5P3T3
      Related
      ENSOARP00020005965.2, ENSOART00020007209.2
      Conserved Domains (3) summary
      cd09376
      Location:93 → 148
      LIM2_Lhx3_Lhx4; The second LIM domain of Lhx3-Lhx4 family
      cd09467
      Location:31 → 85
      LIM1_Lhx3b; The first LIM domain of Lhx3b
      cd00086
      Location:161 → 219
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

    2. XM_027966194.3 → XP_027821995.2  LIM/homeobox protein Lhx3 isoform X1

      UniProtKB/TrEMBL
      A0A836A8P5
      Related
      ENSOARP00020005984.2, ENSOART00020007235.2
      Conserved Domains (3) summary
      cd09376
      Location:95 → 150
      LIM2_Lhx3_Lhx4; The second LIM domain of Lhx3-Lhx4 family
      cd09467
      Location:33 → 87
      LIM1_Lhx3b; The first LIM domain of Lhx3b
      cd00086
      Location:163 → 221
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    Nucleotide Protein Strain
    Heading Accession and Version

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