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    USP2 ubiquitin specific peptidase 2 [ Ovis aries (sheep) ]

    Gene ID: 101109478, updated on 8-Mar-2024

    Summary

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    Gene symbol
    USP2
    Gene description
    ubiquitin specific peptidase 2
    See related
    EnsemblRapid:ENSOARG00020015401
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 15
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 15 NC_056068.1 (29646276..29671723, complement)

    Chromosome 15 - NC_056068.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 5 Neighboring gene membrane frizzled-related protein Neighboring gene uncharacterized LOC121816678 Neighboring gene uncharacterized LOC105602204 Neighboring gene Thy-1 cell surface antigen

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056068.1 Chromosome 15 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056068.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      29646276..29671723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042232990.1 → XP_042088924.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

      UniProtKB/TrEMBL
      A0A836CY02, W5Q333
      Related
      ENSOARP00020044707.1, ENSOART00020072690.1
      Conserved Domains (2) summary
      COG5560
      Location:266 → 446
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:269 → 598
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    2. XM_042232987.1 → XP_042088921.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      Related
      ENSOARP00020020439.2, ENSOART00020024644.2
      Conserved Domains (2) summary
      COG5560
      Location:328 → 508
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:331 → 660
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    3. XM_060399750.1 → XP_060255733.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

      UniProtKB/TrEMBL
      A0A836CY02, W5Q333

    4. XM_042232988.1 → XP_042088922.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      Related
      ENSOARP00020043261.1, ENSOART00020057118.1
      Conserved Domains (2) summary
      COG5560
      Location:328 → 508
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:331 → 660
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    5. XM_060399751.1 → XP_060255734.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

      UniProtKB/TrEMBL
      A0A836CY02, W5Q333

    6. XM_027979322.2 → XP_027835123.2  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

      UniProtKB/TrEMBL
      A0A836CY02, W5Q333
      Conserved Domains (2) summary
      COG5560
      Location:266 → 446
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:269 → 598
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    7. XM_042232986.1 → XP_042088920.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      Conserved Domains (2) summary
      COG5560
      Location:328 → 508
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:331 → 660
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    8. XM_042232989.2 → XP_042088923.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      Conserved Domains (2) summary
      COG5560
      Location:328 → 508
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:331 → 660
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    9. XM_042232991.1 → XP_042088925.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X3

      Related
      ENSOARP00020020510.2, ENSOART00020024725.2
      Conserved Domains (1) summary
      pfam00443
      Location:58 → 387
      UCH; Ubiquitin carboxyl-terminal hydrolase
    Nucleotide Protein Strain
    Heading Accession and Version

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