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    HSCB HscB mitochondrial iron-sulfur cluster cochaperone [ Ovis aries (sheep) ]

    Gene ID: 101106463, updated on 8-Mar-2024

    Summary

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    Gene symbol
    HSCB
    Gene description
    HscB mitochondrial iron-sulfur cluster cochaperone
    See related
    EnsemblRapid:ENSOARG00020008236
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    See HSCB in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 17 NC_056070.1 (68187506..68196822)

    Chromosome 17 - NC_056070.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol transfer protein beta Neighboring gene tetratricopeptide repeat domain 28 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene checkpoint kinase 2 Neighboring gene coiled-coil domain containing 117 Neighboring gene X-box binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056070.1 Chromosome 17 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in [2Fe-2S] cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein complex oligomerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    iron-sulfur cluster co-chaperone protein HscB
    Names
    HscB iron-sulfur cluster co-chaperone homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056070.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      68187506..68196822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027956685.3 → XP_027812486.1  iron-sulfur cluster co-chaperone protein HscB isoform X2

      Related
      ENSOARP00020010433.1, ENSOART00020012674.2

    2. XM_004017457.5 → XP_004017506.1  iron-sulfur cluster co-chaperone protein HscB isoform X1

      UniProtKB/TrEMBL
      A0A6P3EBL5, A0A835ZQ65, W5NXH4
      Related
      ENSOARP00020010409.1, ENSOART00020012643.2
      Conserved Domains (3) summary
      cd06257
      Location:72 → 131
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
      PRK03578
      Location:68 → 228
      hscB; co-chaperone HscB; Provisional
      pfam07743
      Location:157 → 229
      HSCB_C; HSCB C-terminal oligomerization domain

    3. XM_027956686.2 → XP_027812487.1  iron-sulfur cluster co-chaperone protein HscB isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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