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    IFIH1 interferon induced with helicase C domain 1 [ Ovis aries (sheep) ]

    Gene ID: 101106234, updated on 8-Mar-2024

    Summary

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    Gene symbol
    IFIH1
    Gene description
    interferon induced with helicase C domain 1
    See related
    EnsemblRapid:ENSOARG00020010727
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (147486580..147546647)

    Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132659316 Neighboring gene uncharacterized LOC132659315 Neighboring gene uncharacterized LOC132659314 Neighboring gene fibroblast activation protein alpha Neighboring gene glucagon

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interferon-beta production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon-induced helicase C domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      147486580..147546647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004004655.4 → XP_004004704.1  interferon-induced helicase C domain-containing protein 1

      See identical proteins and their annotated locations for XP_004004704.1

      UniProtKB/TrEMBL
      A0A6P3E9S4, W5P823, W5P825
      Related
      ENSOARP00020013826.1, ENSOART00020016740.2
      Conserved Domains (7) summary
      COG1111
      Location:308 → 870
      MPH1; ERCC4-related helicase [Replication, recombination and repair]
      cd08818
      Location:9 → 100
      CARD_MDA5_r1; Caspase activation and recruitment domain found in MDA5, first repeat
      cd15807
      Location:897 → 1013
      MDA5_C; C-terminal domain of Melanoma differentiation-associated protein 5, a cytoplasmic viral RNA receptor
      cd12090
      Location:547 → 691
      MDA5_ID; Insert domain of MDA5
      pfam00271
      Location:695 → 820
      Helicase_C; Helicase conserved C-terminal domain
      pfam04851
      Location:304 → 490
      ResIII; Type III restriction enzyme, res subunit
      cl14633
      Location:112 → 201
      DD; Death Domain Superfamily of protein-protein interaction domains
    Nucleotide Protein Strain
    Heading Accession and Version

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