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    TRIM23 tripartite motif containing 23 [ Ovis aries (sheep) ]

    Gene ID: 101102930, updated on 8-Mar-2024

    Summary

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    Gene symbol
    TRIM23
    Gene description
    tripartite motif containing 23
    See related
    EnsemblRapid:ENSOARG00020005534
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 16
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 16 NC_056069.1 (14050688..14085343)

    Chromosome 16 - NC_056069.1Genomic Context describing neighboring genes Neighboring gene prefoldin subunit 6-like Neighboring gene trafficking protein particle complex subunit 13 Neighboring gene shieldin complex subunit 3 Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene centromere protein K Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056069.1 Chromosome 16 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM23

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056069.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      14050688..14085343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004016933.6 → XP_004016982.1  E3 ubiquitin-protein ligase TRIM23 isoform X1

      See identical proteins and their annotated locations for XP_004016982.1

      UniProtKB/TrEMBL
      W5P8B2
      Related
      ENSOARP00020007033.1, ENSOART00020008511.2
      Conserved Domains (5) summary
      smart00336
      Location:173 → 219
      BBOX; B-Box-type zinc finger
      cd04158
      Location:406 → 574
      ARD1; (ADP-ribosylation factor domain protein 1 (ARD1)
      cd00021
      Location:125 → 168
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      pfam13445
      Location:31 → 73
      zf-RING_UBOX; RING-type zinc-finger
      cl23765
      Location:226 → 370
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    2. XM_060400386.1 → XP_060256369.1  E3 ubiquitin-protein ligase TRIM23 isoform X2

    3. XM_012096834.5 → XP_011952224.1  E3 ubiquitin-protein ligase TRIM23 isoform X3

      See identical proteins and their annotated locations for XP_011952224.1

      Conserved Domains (2) summary
      smart00502
      Location:1 → 66
      BBC; B-Box C-terminal domain
      cd04158
      Location:102 → 270
      ARD1; (ADP-ribosylation factor domain protein 1 (ARD1)

    4. XM_060400387.1 → XP_060256370.1  E3 ubiquitin-protein ligase TRIM23 isoform X3

    5. XM_042233738.2 → XP_042089672.1  E3 ubiquitin-protein ligase TRIM23 isoform X3

      Conserved Domains (2) summary
      smart00502
      Location:1 → 66
      BBC; B-Box C-terminal domain
      cd04158
      Location:102 → 270
      ARD1; (ADP-ribosylation factor domain protein 1 (ARD1)
    Nucleotide Protein Strain
    Heading Accession and Version

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