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    MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase [ Felis catus (domestic cat) ]

    Gene ID: 101098359, updated on 8-Mar-2024

    Summary

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    Official Symbol
    MTRR
    Official Full Name
    5-methyltetrahydrofolate-homocysteine methyltransferase reductase
    Primary source
    VGNC:VGNC:68355
    See related
    EnsemblRapid:ENSFCTG00005015994
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: A1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A1 NC_058368.1 (233289364..233344888, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A1 NC_018723.3 (236033362..236067751, complement)

    Chromosome A1 - NC_058368.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109492288 Neighboring gene uncharacterized LOC111561460 Neighboring gene FAST kinase domains 3 Neighboring gene uncharacterized LOC111556636 Neighboring gene uncharacterized LOC109492295 Neighboring gene cilia and flagella associated protein 90 Neighboring gene adenylate cyclase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables [methionine synthase] reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in homocysteine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in methionine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methionine synthase reductase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058368.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      233289364..233344888 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045038941.1 → XP_044894876.1  methionine synthase reductase isoform X1

      UniProtKB/TrEMBL
      M3WLY4
      Conserved Domains (2) summary
      cd06203
      Location:277 → 702
      methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
      cl00438
      Location:1 → 150
      FMN_red; NADPH-dependent FMN reductase

    2. XM_006928111.5 → XP_006928173.2  methionine synthase reductase isoform X2

      UniProtKB/TrEMBL
      M3WLY4
      Related
      ENSFCTP00005033084.1, ENSFCTT00005046224.1
      Conserved Domains (2) summary
      cd06203
      Location:277 → 696
      methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
      cl00438
      Location:1 → 150
      FMN_red; NADPH-dependent FMN reductase

    3. XM_019812938.3 → XP_019668497.2  methionine synthase reductase isoform X1

      UniProtKB/TrEMBL
      M3WLY4
      Related
      ENSFCTP00005032788.1, ENSFCTT00005045862.1
      Conserved Domains (2) summary
      cd06203
      Location:277 → 702
      methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
      cl00438
      Location:1 → 150
      FMN_red; NADPH-dependent FMN reductase

    4. XM_019812943.3 → XP_019668502.2  methionine synthase reductase isoform X4

      UniProtKB/TrEMBL
      M3WLY4
      Related
      ENSFCTP00005032925.1, ENSFCTT00005046038.1
      Conserved Domains (2) summary
      cd06203
      Location:277 → 641
      methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
      cl00438
      Location:1 → 150
      FMN_red; NADPH-dependent FMN reductase

    5. XM_045038947.1 → XP_044894882.1  methionine synthase reductase isoform X3

      UniProtKB/TrEMBL
      A0A337SJZ7
      Related
      ENSFCTP00005032656.1, ENSFCTT00005045687.1
      Conserved Domains (2) summary
      cd06203
      Location:248 → 673
      methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
      cl00438
      Location:24 → 121
      FMN_red; NADPH-dependent FMN reductase
    Nucleotide Protein
    Heading Accession and Version

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