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    MAPK8 mitogen-activated protein kinase 8 [ Felis catus (domestic cat) ]

    Gene ID: 101091310, updated on 8-Mar-2024

    Summary

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    Official Symbol
    MAPK8
    Official Full Name
    mitogen-activated protein kinase 8
    Primary source
    VGNC:VGNC:68172
    See related
    EnsemblRapid:ENSFCTG00005005215
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: D2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D2 NC_058378.1 (46198317..46296396)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D2 NC_018733.3 (48283021..48384079)

    Chromosome D2 - NC_058378.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109492562 Neighboring gene 5S ribosomal RNA Neighboring gene FERM and PDZ domain containing 2 Neighboring gene uncharacterized LOC109492564 Neighboring gene Rho GTPase activating protein 22 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058378.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      46198317..46296396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023240656.2 → XP_023096424.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2I2UA34, A0A2I2V255
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    2. XM_045040293.1 → XP_044896228.1  mitogen-activated protein kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A337S2P6
      Related
      ENSFCTP00005009586.1, ENSFCTT00005014412.1
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    3. XM_023240655.2 → XP_023096423.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2I2UA34, A0A2I2V255
      Related
      ENSFCTP00005009640.1, ENSFCTT00005014466.1
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    4. XM_023240657.2 → XP_023096425.1  mitogen-activated protein kinase 8 isoform X3

      UniProtKB/TrEMBL
      A0A2I2UA34, A0A337S0H7
      Related
      ENSFCTP00005009564.1, ENSFCTT00005014390.1
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    5. XM_003994155.6 → XP_003994204.1  mitogen-activated protein kinase 8 isoform X1

      See identical proteins and their annotated locations for XP_003994204.1

      UniProtKB/TrEMBL
      A0A2I2UA34, A0A2I2V255
      Related
      ENSFCTP00005009537.1, ENSFCTT00005014363.1
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

    6. XM_045040294.1 → XP_044896229.1  mitogen-activated protein kinase 8 isoform X1

      UniProtKB/TrEMBL
      A0A2I2UA34, A0A2I2V255
      Conserved Domains (1) summary
      cd07850
      Location:25 → 360
      STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase
    Nucleotide Protein
    Heading Accession and Version

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