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    RAD18 RAD18 E3 ubiquitin protein ligase [ Felis catus (domestic cat) ]

    Gene ID: 101081963, updated on 8-Mar-2024

    Summary

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    Official Symbol
    RAD18
    Official Full Name
    RAD18 E3 ubiquitin protein ligase
    Primary source
    VGNC:VGNC:64477
    See related
    EnsemblRapid:ENSFCTG00005001875
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: A2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A2 NC_058369.1 (50325773..50436139, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A2 NC_018724.3 (50241436..50353037, complement)

    Chromosome A2 - NC_058369.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123383768 Neighboring gene oxytocin receptor Neighboring gene SLIT-ROBO Rho GTPase activating protein 3 Neighboring gene uncharacterized LOC102899285 Neighboring gene THUMP domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in postreplication repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein monoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rad6-Rad18 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RAD18
    Names
    RAD18 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058369.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      50325773..50436139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_019824935.2 → XP_019680494.1  E3 ubiquitin-protein ligase RAD18 isoform X2

      UniProtKB/TrEMBL
      A0A5F5XU25
      Related
      ENSFCTP00005002843.1, ENSFCTT00005004823.1
      Conserved Domains (1) summary
      cl28410
      Location:13 → 363
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

    2. XM_003982447.5 → XP_003982496.2  E3 ubiquitin-protein ligase RAD18 isoform X1

      UniProtKB/TrEMBL
      M3XD01
      Related
      ENSFCTP00005002840.1, ENSFCTT00005004820.1
      Conserved Domains (4) summary
      smart00734
      Location:201 → 224
      ZnF_Rad18; Rad18-like CCHC zinc finger
      cd00162
      Location:25 → 63
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      TIGR00599
      Location:13 → 363
      rad18; DNA repair protein rad18
      pfam02037
      Location:248 → 282
      SAP; SAP domain

    3. XM_019824936.2 → XP_019680495.1  E3 ubiquitin-protein ligase RAD18 isoform X3

      Conserved Domains (1) summary
      cl28410
      Location:13 → 363
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

    4. XM_045051894.1 → XP_044907829.1  E3 ubiquitin-protein ligase RAD18 isoform X4

      Conserved Domains (1) summary
      TIGR00599
      Location:13 → 363
      rad18; DNA repair protein rad18

    RNA

    1. XR_002153348.3 RNA Sequence

    2. XR_006593950.1 RNA Sequence

      Related
      ENSFCTT00005004806.1

    3. XR_002153346.3 RNA Sequence

    4. XR_006593949.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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