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    SPPL2C signal peptide peptidase like 2C [ Felis catus (domestic cat) ]

    Gene ID: 101081094, updated on 8-Mar-2024

    Summary

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    Official Symbol
    SPPL2C
    Official Full Name
    signal peptide peptidase like 2C
    Primary source
    VGNC:VGNC:97643
    See related
    EnsemblRapid:ENSFCTG00005027145
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: E1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) E1 NC_058381.1 (44460473..44462709)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) E1 NC_018736.3 (45974123..45976369)

    Chromosome E1 - NC_058381.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102899185 Neighboring gene uncharacterized LOC123381949 Neighboring gene corticotropin releasing hormone receptor 1 Neighboring gene uncharacterized LOC109494402 Neighboring gene microtubule associated protein tau Neighboring gene KAT8 regulatory NSL complex subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane protein proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi-associated vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic side of endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lumenal side of endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal peptide peptidase-like 2C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058381.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      44460473..44462709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011289275.4 → XP_011287577.3  signal peptide peptidase-like 2C

      UniProtKB/TrEMBL
      A0A2I2UCM6
      Related
      ENSFCTP00005053767.1, ENSFCTT00005076694.1
      Conserved Domains (2) summary
      cl28883
      Location:39 → 176
      PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...
      cl01342
      Location:248 → 529
      Peptidase_A22B; Signal peptide peptidase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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