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    Prkg1 protein kinase cGMP-dependent 1 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100734084, updated on 3-Apr-2024

    Summary

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    Gene symbol
    Prkg1
    Gene description
    protein kinase cGMP-dependent 1
    See related
    Ensembl:ENSCPOG00000005830
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947511.1 (12126751..13286258)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176404.1 (3190544..4343090)

    NW_026947511.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106028518 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene cleavage stimulation factor subunit 2 tau variant Neighboring gene single-stranded DNA-binding protein 2-like Neighboring gene tRNA methyltransferase 10 homolog A-like Neighboring gene dickkopf WNT signaling pathway inhibitor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cGMP-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cGMP-dependent protein kinase 1
    Names
    protein kinase, cGMP-dependent, type I

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947511.1 Reference mCavPor4.1

      Range
      12126751..13286258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063239051.1 → XP_063095121.1  cGMP-dependent protein kinase 1 isoform X2

    2. XM_003473935.5 → XP_003473983.1  cGMP-dependent protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A286XKF5, H0V6E2
      Related
      ENSCPOP00000025783.1
      Conserved Domains (6) summary
      PTZ00263
      Location:368 → 676
      PTZ00263; protein kinase A catalytic subunit; Provisional
      cd12086
      Location:4 → 55
      DD_cGKI-beta; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I beta
      smart00133
      Location:636 → 679
      S_TK_X; Extension to Ser/Thr-type protein kinases
      COG0664
      Location:230 → 336
      Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
      cd00038
      Location:237 → 341
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd05572
      Location:381 → 641
      STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)

    3. XM_023566675.2 → XP_023422443.1  cGMP-dependent protein kinase 1 isoform X3

      Conserved Domains (2) summary
      smart00133
      Location:353 → 396
      S_TK_X; Extension to Ser/Thr-type protein kinases
      cd05572
      Location:98 → 358
      STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)
    Nucleotide Protein
    Heading Accession and Version

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