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    Pxn paxillin [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100732427, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Pxn
    Gene description
    paxillin
    See related
    Ensembl:ENSCPOG00000000411
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947499.1 (16737010..16789792, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176415.1 (5353841..5367953, complement)

    NW_026947499.1Genomic Context describing neighboring genes Neighboring gene GCN1 activator of EIF2AK4 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene ribosomal protein lateral stalk subunit P0 Neighboring gene uncharacterized LOC134470653 Neighboring gene small ribosomal subunit protein eS4, X isoform-like Neighboring gene U4 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in endothelial cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    paxillin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947499.1 Reference mCavPor4.1

      Range
      16737010..16789792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063225762.1 → XP_063081832.1  paxillin isoform X6

    2. XM_063225761.1 → XP_063081831.1  paxillin isoform X5

    3. XM_063225760.1 → XP_063081830.1  paxillin isoform X4

    4. XM_063225758.1 → XP_063081828.1  paxillin isoform X2

    5. XM_063225757.1 → XP_063081827.1  paxillin isoform X1

    6. XM_063225759.1 → XP_063081829.1  paxillin isoform X3

    7. XM_013141925.2 → XP_012997379.1  paxillin isoform X3

      See identical proteins and their annotated locations for XP_012997379.1

      Conserved Domains (5) summary
      cd09338
      Location:833 → 885
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09407
      Location:774 → 825
      LIM2_Paxillin; The second LIM domain of paxillin
      cd09411
      Location:892 → 943
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:715 → 767
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:1 → 120
      Paxillin; Paxillin family
    Nucleotide Protein
    Heading Accession and Version

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