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    Amfr autocrine motility factor receptor [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100729655, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Amfr
    Gene description
    autocrine motility factor receptor
    See related
    Ensembl:ENSCPOG00000004466
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947487.1 (83411428..83450479, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176397.1 (25495388..25534281)

    NW_026947487.1Genomic Context describing neighboring genes Neighboring gene carboxylesterase 5A Neighboring gene uncharacterized LOC134475617 Neighboring gene G protein subunit alpha o1 Neighboring gene uncharacterized LOC134475744 Neighboring gene nudix hydrolase 21 Neighboring gene 2-oxoglutarate and iron dependent oxygenase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase AMFR

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947487.1 Reference mCavPor4.1

      Range
      83411428..83450479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003472091.4 → XP_003472139.1  E3 ubiquitin-protein ligase AMFR

      UniProtKB/TrEMBL
      H0V377
      Related
      ENSCPOP00000004029.2
      Conserved Domains (3) summary
      COG5243
      Location:86 → 382
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      cd14421
      Location:458 → 498
      CUE_AMFR; CUE domain found in autocrine motility factor receptor (AMFR) and similar proteins
      pfam13639
      Location:339 → 379
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version

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