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    PINK1 PTEN induced kinase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 100688445, updated on 8-Mar-2024

    Summary

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    Official Symbol
    PINK1provided by VGNC
    Official Full Name
    PTEN induced kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:44567
    See related
    Ensembl:ENSCAFG00845002503
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (78842969..78861096, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (74790397..74808514, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (77677116..77695256, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (75661680..75679782, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (76673498..76691638, complement)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 17 Neighboring gene dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Neighboring gene uncharacterized LOC119870450 Neighboring gene cytidine deaminase Neighboring gene family with sequence similarity 43 member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy of mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of mitochondrial fission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PINK1, mitochondrial
    Names
    PTEN induced putative kinase 1
    XP_013962588.2
    XP_038326803.1
    XP_038387680.1
    XP_038451919.1
    XP_038516010.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      78842969..78861096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038660082.1 → XP_038516010.1  serine/threonine-protein kinase PINK1, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0K645, A0A8C0MG24, A0A8C0Q5E0, A0A8I3MFF8
      Related
      ENSCAFP00845003537.1, ENSCAFT00845004422.1
      Conserved Domains (2) summary
      cd14018
      Location:165 → 513
      STKc_PINK1; Catalytic domain of the Serine/Threonine protein kinase, Pten INduced Kinase 1
      cl23947
      Location:146 → 204
      DUF3653; Phage protein

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      75661680..75679782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038470875.1 → XP_038326803.1  serine/threonine-protein kinase PINK1, mitochondrial

      Conserved Domains (2) summary
      cd14018
      Location:165 → 513
      STKc_PINK1; Catalytic domain of the Serine/Threonine protein kinase, Pten INduced Kinase 1
      cl23947
      Location:146 → 204
      DUF3653; Phage protein

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      76673498..76691638 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038595991.1 → XP_038451919.1  serine/threonine-protein kinase PINK1, mitochondrial

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      77677116..77695256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038531752.1 → XP_038387680.1  serine/threonine-protein kinase PINK1, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0MG24

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      74790397..74808514 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014107113.2 → XP_013962588.2  serine/threonine-protein kinase PINK1, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0K645, A0A8C0MG24, A0A8C0Q5E0, A0A8I3MFF8
      Conserved Domains (2) summary
      cd14018
      Location:165 → 513
      STKc_PINK1; Catalytic domain of the Serine/Threonine protein kinase, Pten INduced Kinase 1
      cl23947
      Location:146 → 204
      DUF3653; Phage protein
    Nucleotide Protein
    Heading Accession and Version

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