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    ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100355552, updated on 8-Mar-2024

    Summary

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    Gene symbol
    ADAMTS6
    Gene description
    ADAM metallopeptidase with thrombospondin type 1 motif 6
    See related
    Ensembl:ENSOCUG00000001525
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 11 NC_067384.1 (7949974..8266063)

    Chromosome 11 - NC_067384.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene centromere protein K Neighboring gene uncharacterized LOC127492812 Neighboring gene uncharacterized LOC103349635 Neighboring gene uncharacterized LOC127492813

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067384.1 Chromosome 11 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067384.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      7949974..8266063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051853704.1 → XP_051709664.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X10

    2. XM_051853700.1 → XP_051709660.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X5

    3. XM_051853699.1 → XP_051709659.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X4

    4. XM_051853696.1 → XP_051709656.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1

    5. XM_051853698.1 → XP_051709658.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X3

    6. XM_051853702.1 → XP_051709662.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X8

    7. XM_008262276.3 → XP_008260498.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X6

      Conserved Domains (6) summary
      smart00209
      Location:971 → 1018
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:249 → 464
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:249 → 467
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:68 → 189
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:668 → 778
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1032 → 1064
      PLAC; PLAC (protease and lacunin) domain

    8. XM_051853703.1 → XP_051709663.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X9

    9. XM_051853705.1 → XP_051709665.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X11

    10. XM_002714062.4 → XP_002714108.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X2

      UniProtKB/TrEMBL
      G1SFL4
      Related
      ENSOCUP00000001315.2
      Conserved Domains (6) summary
      smart00209
      Location:560 → 612
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:249 → 464
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:249 → 467
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:68 → 189
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:718 → 828
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1082 → 1114
      PLAC; PLAC (protease and lacunin) domain

    11. XM_051853701.1 → XP_051709661.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X7

    12. XM_051853697.1 → XP_051709657.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1

    RNA

    1. XR_007922586.1 RNA Sequence

    2. XR_007922587.1 RNA Sequence

    3. XR_007922584.1 RNA Sequence

    4. XR_007922588.1 RNA Sequence

    5. XR_007922585.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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