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    SORBS2 sorbin and SH3 domain containing 2 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100344295, updated on 3-Apr-2024

    Summary

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    Gene symbol
    SORBS2
    Gene description
    sorbin and SH3 domain containing 2
    See related
    Ensembl:ENSOCUG00000005816
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (63509400..63894883, complement)

    Chromosome 2 - NC_067375.1Genomic Context describing neighboring genes Neighboring gene PDZ and LIM domain 3 Neighboring gene uncharacterized LOC103345694 Neighboring gene uncharacterized LOC127487574 Neighboring gene toll like receptor 3 Neighboring gene family with sequence similarity 149 member A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067375.1 Chromosome 2 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sorbin and SH3 domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067375.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      63509400..63894883 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051833267.1 → XP_051689227.1  sorbin and SH3 domain-containing protein 2 isoform X1

    2. XM_051833270.1 → XP_051689230.1  sorbin and SH3 domain-containing protein 2 isoform X1

    3. XM_051833316.1 → XP_051689276.1  sorbin and SH3 domain-containing protein 2 isoform X8

    4. XM_051833288.1 → XP_051689248.1  sorbin and SH3 domain-containing protein 2 isoform X3

    5. XM_051833356.1 → XP_051689316.1  sorbin and SH3 domain-containing protein 2 isoform X10

    6. XM_051833308.1 → XP_051689268.1  sorbin and SH3 domain-containing protein 2 isoform X7

    7. XM_051833265.1 → XP_051689225.1  sorbin and SH3 domain-containing protein 2 isoform X1

    8. XM_051833311.1 → XP_051689271.1  sorbin and SH3 domain-containing protein 2 isoform X8

    9. XM_051833283.1 → XP_051689243.1  sorbin and SH3 domain-containing protein 2 isoform X3

    10. XM_051833334.1 → XP_051689294.1  sorbin and SH3 domain-containing protein 2 isoform X10

    11. XM_051833296.1 → XP_051689256.1  sorbin and SH3 domain-containing protein 2 isoform X7

    12. XM_051833291.1 → XP_051689251.1  sorbin and SH3 domain-containing protein 2 isoform X5

    13. XM_051833290.1 → XP_051689250.1  sorbin and SH3 domain-containing protein 2 isoform X4

    14. XM_051833361.1 → XP_051689321.1  sorbin and SH3 domain-containing protein 2 isoform X11

    15. XM_051833324.1 → XP_051689284.1  sorbin and SH3 domain-containing protein 2 isoform X9

    16. XM_051833294.1 → XP_051689254.1  sorbin and SH3 domain-containing protein 2 isoform X6

    17. XM_051833275.1 → XP_051689235.1  sorbin and SH3 domain-containing protein 2 isoform X2

    18. XM_051833245.1 → XP_051689205.1  sorbin and SH3 domain-containing protein 2 isoform X1

    19. XM_051833345.1 → XP_051689305.1  sorbin and SH3 domain-containing protein 2 isoform X10

    20. XM_051833301.1 → XP_051689261.1  sorbin and SH3 domain-containing protein 2 isoform X7

    21. XM_051833259.1 → XP_051689219.1  sorbin and SH3 domain-containing protein 2 isoform X1

    22. XM_051833252.1 → XP_051689212.1  sorbin and SH3 domain-containing protein 2 isoform X1

    23. XM_051833389.1 → XP_051689349.1  sorbin and SH3 domain-containing protein 2 isoform X15

    24. XM_051833382.1 → XP_051689342.1  sorbin and SH3 domain-containing protein 2 isoform X14

    25. XM_051833364.1 → XP_051689324.1  sorbin and SH3 domain-containing protein 2 isoform X12

    26. XM_051833409.1 → XP_051689369.1  sorbin and SH3 domain-containing protein 2 isoform X17

    27. XM_051833394.1 → XP_051689354.1  sorbin and SH3 domain-containing protein 2 isoform X17

    28. XM_051833391.1 → XP_051689351.1  sorbin and SH3 domain-containing protein 2 isoform X16

    29. XM_051833373.1 → XP_051689333.1  sorbin and SH3 domain-containing protein 2 isoform X13

    30. XM_051833427.1 → XP_051689387.1  sorbin and SH3 domain-containing protein 2 isoform X19

    31. XM_051833402.1 → XP_051689362.1  sorbin and SH3 domain-containing protein 2 isoform X17

    32. XM_051833398.1 → XP_051689358.1  sorbin and SH3 domain-containing protein 2 isoform X17

    33. XM_051833431.1 → XP_051689391.1  sorbin and SH3 domain-containing protein 2 isoform X22

    34. XM_051833420.1 → XP_051689380.1  sorbin and SH3 domain-containing protein 2 isoform X18

    35. XM_051833430.1 → XP_051689390.1  sorbin and SH3 domain-containing protein 2 isoform X21

    36. XM_051833429.1 → XP_051689389.1  sorbin and SH3 domain-containing protein 2 isoform X20

    37. XM_051833438.1 → XP_051689398.1  sorbin and SH3 domain-containing protein 2 isoform X23

    38. XM_051833456.1 → XP_051689416.1  sorbin and SH3 domain-containing protein 2 isoform X26

    39. XM_051833449.1 → XP_051689409.1  sorbin and SH3 domain-containing protein 2 isoform X24

    40. XM_051833467.1 → XP_051689427.1  sorbin and SH3 domain-containing protein 2 isoform X27

    41. XM_008250726.3 → XP_008248948.1  sorbin and SH3 domain-containing protein 2 isoform X25

      UniProtKB/TrEMBL
      A0A5F9DU28, G1SPQ9
      Related
      ENSOCUP00000005044.3
      Conserved Domains (4) summary
      smart00459
      Location:167 → 217
      Sorb; Sorbin homologous domain
      cd11917
      Location:1140 → 1200
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1041 → 1097
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:966 → 1020
      SH3; Src Homology 3 domain superfamily

    42. XM_051833260.1 → XP_051689220.1  sorbin and SH3 domain-containing protein 2 isoform X1

    43. XM_008250735.3 → XP_008248957.1  sorbin and SH3 domain-containing protein 2 isoform X29

      UniProtKB/TrEMBL
      A0A5F9CQA8
      Related
      ENSOCUP00000035847.1
      Conserved Domains (4) summary
      cd11917
      Location:944 → 1004
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:845 → 901
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl02617
      Location:4 → 31
      Sorb; Sorbin homologous domain
      cl17036
      Location:770 → 824
      SH3; Src Homology 3 domain superfamily

    44. XM_051833478.1 → XP_051689438.1  sorbin and SH3 domain-containing protein 2 isoform X28

    45. XM_017338658.2 → XP_017194147.1  sorbin and SH3 domain-containing protein 2 isoform X31

      UniProtKB/TrEMBL
      A0A5F9C4D5

    46. XM_051833488.1 → XP_051689448.1  sorbin and SH3 domain-containing protein 2 isoform X30

    47. XM_008250741.3 → XP_008248963.1  sorbin and SH3 domain-containing protein 2 isoform X32

      UniProtKB/TrEMBL
      A0A5F9CWH0, A0A5F9D3F7
      Related
      ENSOCUP00000038150.1
      Conserved Domains (3) summary
      smart00459
      Location:167 → 217
      Sorb; Sorbin homologous domain
      cd11923
      Location:530 → 586
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:629 → 689
      SH3; Src Homology 3 domain superfamily

    48. XM_008250747.3 → XP_008248969.1  sorbin and SH3 domain-containing protein 2 isoform X33

      UniProtKB/TrEMBL
      A0A5F9D3F7
      Conserved Domains (3) summary
      smart00459
      Location:167 → 212
      Sorb; Sorbin homologous domain
      cd11923
      Location:496 → 552
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:595 → 655
      SH3; Src Homology 3 domain superfamily

    49. XM_051833505.1 → XP_051689465.1  sorbin and SH3 domain-containing protein 2 isoform X35

    50. XM_008250754.3 → XP_008248976.1  sorbin and SH3 domain-containing protein 2 isoform X34

      Conserved Domains (3) summary
      cd11923
      Location:330 → 386
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl02617
      Location:4 → 36
      Sorb; Sorbin homologous domain
      cl17036
      Location:429 → 489
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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