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    GLS glutaminase [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100343465, updated on 3-Apr-2024

    Summary

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    Gene symbol
    GLS
    Gene description
    glutaminase
    See related
    Ensembl:ENSOCUG00000002448
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    See GLS in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 7 NC_067380.1 (42199277..42288616, complement)

    Chromosome 7 - NC_067380.1Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 4 Neighboring gene uncharacterized LOC103348800 Neighboring gene signal transducer and activator of transcription 1 Neighboring gene serine protease 58 Neighboring gene NGFI-A binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067380.1 Chromosome 7 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glutamine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutaminase kidney isoform, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067380.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      42199277..42288616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002712344.4 → XP_002712390.1  glutaminase kidney isoform, mitochondrial isoform X1

      UniProtKB/TrEMBL
      G1SHK8
      Related
      ENSOCUP00000002118.3
      Conserved Domains (4) summary
      cd00204
      Location:558 → 643
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam04960
      Location:245 → 531
      Glutaminase; Glutaminase
      pfam13637
      Location:588 → 640
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:558 → 584
      ANK; ANK repeat [structural motif]

    2. XM_051848348.1 → XP_051704308.1  glutaminase kidney isoform, mitochondrial isoform X4

    3. XM_051848346.1 → XP_051704306.1  glutaminase kidney isoform, mitochondrial isoform X2

    4. XM_051848347.1 → XP_051704307.1  glutaminase kidney isoform, mitochondrial isoform X3

    Nucleotide Protein
    Heading Accession and Version

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