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    MAP2K4 mitogen-activated protein kinase kinase 4 [ Equus caballus (horse) ]

    Gene ID: 100073094, updated on 8-Mar-2024

    Summary

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    Official Symbol
    MAP2K4provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase 4provided by VGNC
    Primary source
    VGNC:VGNC:19927
    See related
    Ensembl:ENSECAG00000025163
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (54691894..54828149)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 11 NC_009154.2 (54348042..54477947)

    Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene dynein axonemal heavy chain 9 Neighboring gene zinc finger protein 18 Neighboring gene microRNA mir-744 Neighboring gene uncharacterized LOC102148178 Neighboring gene uncharacterized LOC106782894

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual specificity mitogen-activated protein kinase kinase 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009154.3 Reference EquCab3.0 Primary Assembly

      Range
      54691894..54828149
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023653527.1 → XP_023509295.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X1

      UniProtKB/TrEMBL
      A0A9L0S1M1, A0A9L0SLJ1
      Related
      ENSECAP00000067954.1, ENSECAT00000117965.1
      Conserved Domains (1) summary
      cd06616
      Location:106 → 396
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

    2. XM_023653528.1 → XP_023509296.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X2

      UniProtKB/TrEMBL
      A0A5F5PRU9, A0A9L0SLJ1
      Related
      ENSECAP00000051385.2, ENSECAT00000074859.2
      Conserved Domains (1) summary
      cd06616
      Location:95 → 385
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

    3. XM_023653529.1 → XP_023509297.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X3

      UniProtKB/TrEMBL
      A0A9L0SLJ1
      Conserved Domains (1) summary
      cd06616
      Location:34 → 324
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4
    Nucleotide Protein
    Heading Accession and Version

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