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    ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif 16 [ Equus caballus (horse) ]

    Gene ID: 100071544, updated on 8-Mar-2024

    Summary

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    Official Symbol
    ADAMTS16provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 16provided by VGNC
    Primary source
    VGNC:VGNC:15065
    See related
    Ensembl:ENSECAG00000000787
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS16 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (54694273..54848611, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 21 NC_009164.2 (53444098..53598250, complement)

    Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 10 Neighboring gene interactor of little elongation complex ELL subunit 1 Neighboring gene dnaJ homolog subfamily A member 1 Neighboring gene uncharacterized LOC111769642

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009164.3 Reference EquCab3.0 Primary Assembly

      Range
      54694273..54848611 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023625872.1 → XP_023481640.1  A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X2

      UniProtKB/TrEMBL
      A0A9L0RK15, A0A9L0S4S1
      Related
      ENSECAP00000069836.1, ENSECAT00000116311.1
      Conserved Domains (5) summary
      smart00209
      Location:610 → 662
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:311 → 512
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01562
      Location:75 → 219
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:767 → 879
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1211 → 1241
      PLAC; PLAC (protease and lacunin) domain

    2. XM_023625871.1 → XP_023481639.1  A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1

      UniProtKB/TrEMBL
      A0A9L0RK15, F6W504
      Related
      ENSECAP00000001447.3, ENSECAT00000002026.3
      Conserved Domains (5) summary
      smart00209
      Location:614 → 666
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:315 → 516
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01562
      Location:79 → 223
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:771 → 883
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1215 → 1245
      PLAC; PLAC (protease and lacunin) domain
    Nucleotide Protein
    Heading Accession and Version

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