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    CUL2 cullin 2 [ Equus caballus (horse) ]

    Gene ID: 100054982, updated on 8-Mar-2024

    Summary

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    Official Symbol
    CUL2provided by VGNC
    Official Full Name
    cullin 2provided by VGNC
    Primary source
    VGNC:VGNC:16967
    See related
    Ensembl:ENSECAG00000015528
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See CUL2 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 29 NC_009172.3 (4230261..4328564)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 29 NC_009172.2 (3221820..3313926)

    Chromosome 29 - NC_009172.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111771172 Neighboring gene cAMP responsive element modulator Neighboring gene uncharacterized LOC111771205 Neighboring gene par-3 family cell polarity regulator Neighboring gene uncharacterized LOC111771170

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cullin-2
    Names
    Cullin-2-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301216.2 → NP_001288145.1  cullin-2

      See identical proteins and their annotated locations for NP_001288145.1

      Status: PROVISIONAL

      Source sequence(s)
      PJAA01000030
      UniProtKB/TrEMBL
      A0A3Q2L9D5, A0A9L0TEB6
      Related
      ENSECAP00000035945.1, ENSECAT00000065579.1
      Conserved Domains (2) summary
      pfam00888
      Location:15 → 643
      Cullin; Cullin family
      pfam10557
      Location:677 → 735
      Cullin_Nedd8; Cullin protein neddylation domain

    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009172.3 Reference EquCab3.0 Primary Assembly

      Range
      4230261..4328564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023631882.1 → XP_023487650.1  cullin-2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2L9D5, A0A9L0TEB6
      Conserved Domains (2) summary
      pfam00888
      Location:15 → 643
      Cullin; Cullin family
      pfam10557
      Location:677 → 735
      Cullin_Nedd8; Cullin protein neddylation domain

    2. XM_023631881.1 → XP_023487649.1  cullin-2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2L9D5, A0A9L0TEB6
      Conserved Domains (2) summary
      pfam00888
      Location:15 → 643
      Cullin; Cullin family
      pfam10557
      Location:677 → 735
      Cullin_Nedd8; Cullin protein neddylation domain

    3. XM_001491887.6 → XP_001491937.1  cullin-2 isoform X1

      See identical proteins and their annotated locations for XP_001491937.1

      UniProtKB/TrEMBL
      A0A3Q2L9D5, A0A9L0TEB6
      Conserved Domains (2) summary
      pfam00888
      Location:15 → 643
      Cullin; Cullin family
      pfam10557
      Location:677 → 735
      Cullin_Nedd8; Cullin protein neddylation domain

    4. XM_005606842.3 → XP_005606899.1  cullin-2 isoform X1

      See identical proteins and their annotated locations for XP_005606899.1

      UniProtKB/TrEMBL
      A0A3Q2L9D5, A0A9L0TEB6
      Conserved Domains (2) summary
      pfam00888
      Location:15 → 643
      Cullin; Cullin family
      pfam10557
      Location:677 → 735
      Cullin_Nedd8; Cullin protein neddylation domain

    5. XM_023631883.1 → XP_023487651.1  cullin-2 isoform X2

      UniProtKB/TrEMBL
      A0A9L0TA87
      Conserved Domains (2) summary
      pfam00888
      Location:2 → 498
      Cullin; Cullin family
      pfam10557
      Location:532 → 590
      Cullin_Nedd8; Cullin protein neddylation domain
    Nucleotide Protein
    Heading Accession and Version

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