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    TLK2 tousled like kinase 2 [ Equus caballus (horse) ]

    Gene ID: 100054465, updated on 8-Mar-2024

    Summary

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    Official Symbol
    TLK2provided by VGNC
    Official Full Name
    tousled like kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:24132
    See related
    Ensembl:ENSECAG00000021279
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (16518022..16630186, complement)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 11 NC_009154.2 (16545720..16655627, complement)

    Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 10 Neighboring gene mannose receptor C-type 2 Neighboring gene uncharacterized LOC111775617 Neighboring gene uncharacterized LOC111775619 Neighboring gene methyltransferase 2A, tRNA N3-cytidine Neighboring gene EF-hand calcium binding domain 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase tousled-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009154.3 Reference EquCab3.0 Primary Assembly

      Range
      16518022..16630186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023652276.1 → XP_023508044.1  serine/threonine-protein kinase tousled-like 2 isoform X3

      UniProtKB/TrEMBL
      A0A5F5PMT7, A0A9L0SZQ2
      Related
      ENSECAP00000049723.2, ENSECAT00000076575.2
      Conserved Domains (2) summary
      COG1196
      Location:179 → 471
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd14041
      Location:401 → 709
      STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

    2. XM_023652274.1 → XP_023508042.1  serine/threonine-protein kinase tousled-like 2 isoform X1

      UniProtKB/TrEMBL
      F6YSV2
      Related
      ENSECAP00000062317.1, ENSECAT00000095380.1
      Conserved Domains (2) summary
      COG1196
      Location:206 → 503
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd14041
      Location:433 → 741
      STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

    3. XM_023652275.1 → XP_023508043.1  serine/threonine-protein kinase tousled-like 2 isoform X2

      UniProtKB/TrEMBL
      A0A9L0SHP1
      Related
      ENSECAP00000062485.1, ENSECAT00000100452.1
      Conserved Domains (2) summary
      COG1196
      Location:174 → 471
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd14041
      Location:401 → 709
      STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2

    4. XM_023652273.1 → XP_023508041.1  serine/threonine-protein kinase tousled-like 2 isoform X1

      UniProtKB/TrEMBL
      F6YSV2
      Related
      ENSECAP00000019195.3, ENSECAT00000023191.3
      Conserved Domains (2) summary
      COG1196
      Location:206 → 503
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd14041
      Location:433 → 741
      STKc_TLK2; Catalytic domain of the Serine/Threonine kinase, Tousled-Like Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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