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    MYLK2 myosin light chain kinase 2 [ Equus caballus (horse) ]

    Gene ID: 100053698, updated on 8-Mar-2024

    Summary

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    Official Symbol
    MYLK2provided by VGNC
    Official Full Name
    myosin light chain kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:58950
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 22
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 22 NC_009165.3 (23458715..23473193)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 22 NC_009165.2 (22828633..22843229)

    Chromosome 22 - NC_009165.3Genomic Context describing neighboring genes Neighboring gene TPX2 microtubule nucleation factor Neighboring gene uncharacterized LOC102149007 Neighboring gene interferon regulatory factor 4 Neighboring gene forkhead box S1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables myosin light chain kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin light chain kinase 2, skeletal/cardiac muscle

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009165.3 Reference EquCab3.0 Primary Assembly

      Range
      23458715..23473193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023626290.1 → XP_023482058.1  myosin light chain kinase 2, skeletal/cardiac muscle

      Conserved Domains (2) summary
      cd14190
      Location:292 → 552
      STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2
      cl26386
      Location:18 → 235
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    Nucleotide Protein
    Heading Accession and Version

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