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    PALS1 protein associated with LIN7 1, MAGUK p55 family member [ Equus caballus (horse) ]

    Gene ID: 100052602, updated on 8-Mar-2024

    Summary

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    Official Symbol
    PALS1provided by VGNC
    Official Full Name
    protein associated with LIN7 1, MAGUK p55 family memberprovided by VGNC
    Primary source
    VGNC:VGNC:20292
    See related
    Ensembl:ENSECAG00000000356
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Also known as
    MPP5
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current EquCab3.0 (GCF_002863925.1) 24 NC_009167.3 (13468734..13558656)
    102 previous assembly EquCab2.0 (GCF_000002305.2) 24 NC_009167.2 (13594284..13657475)

    Chromosome 24 - NC_009167.3Genomic Context describing neighboring genes Neighboring gene gephyrin Neighboring gene golgi associated RAB2 interactor family member 2 Neighboring gene ATPase H+ transporting V1 subunit D Neighboring gene eukaryotic translation initiation factor 2 subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment or maintenance of polarity of embryonic epithelium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in generation of neurons IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in morphogenesis of an epithelial sheet IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MAGUK p55 subfamily member 5
    Names
    membrane palmitoylated protein 5
    membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
    protein associated with LIN7 1, MAGUK family member

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009167.3 Reference EquCab3.0 Primary Assembly

      Range
      13468734..13558656
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023627950.1 → XP_023483718.1  MAGUK p55 subfamily member 5 isoform X1

      UniProtKB/TrEMBL
      A0A9L0T3A8, F7C695
      Related
      ENSECAP00000081665.1, ENSECAT00000098759.1
      Conserved Domains (5) summary
      smart00569
      Location:189 → 238
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12036
      Location:349 → 411
      SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
      smart00072
      Location:491 → 661
      GuKc; Guanylate kinase homologues
      cd00992
      Location:254 → 333
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam09060
      Location:123 → 170
      L27_N

    2. XM_023627951.1 → XP_023483719.1  MAGUK p55 subfamily member 5 isoform X2

      UniProtKB/TrEMBL
      F7C695
      Conserved Domains (5) summary
      smart00569
      Location:155 → 204
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12036
      Location:315 → 377
      SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
      smart00072
      Location:457 → 627
      GuKc; Guanylate kinase homologues
      cd00992
      Location:220 → 299
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam09060
      Location:89 → 136
      L27_N
    Nucleotide Protein
    Heading Accession and Version

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