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    HK1 hexokinase 1 [ Ovis aries (sheep) ]

    Gene ID: 100036759, updated on 3-Apr-2024

    Summary

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    Gene symbol
    HK1
    Gene description
    hexokinase 1
    See related
    EnsemblRapid:ENSOARG00020010440
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 25 NC_056078.1 (24890076..24965830)

    Chromosome 25 - NC_056078.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132658672 Neighboring gene uncharacterized LOC132658673 Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene tachykinin receptor 2 Neighboring gene uncharacterized LOC114110841 Neighboring gene uncharacterized LOC105604969

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056078.1 Chromosome 25 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glucokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glucose binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mannokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glucose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hexokinase-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056078.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      24890076..24965830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_060406861.1 → XP_060262844.1  hexokinase-1 isoform X2

      Related
      ENSOARP00020013630.1, ENSOART00020016493.2

    2. XM_015104404.3 → XP_014959890.2  hexokinase-1 isoform X1

      UniProtKB/TrEMBL
      A0A6P3YPP8, W5P659
      Conserved Domains (3) summary
      PTZ00107
      Location:12 → 460
      PTZ00107; hexokinase; Provisional
      pfam00349
      Location:469 → 667
      Hexokinase_1
      pfam03727
      Location:673 → 907
      Hexokinase_2

    3. XM_042240866.2 → XP_042096800.1  hexokinase-1 isoform X3

      UniProtKB/TrEMBL
      W5P659
      Related
      ENSOARP00020013707.2, ENSOART00020016587.2
      Conserved Domains (1) summary
      PTZ00107
      Location:1 → 432
      PTZ00107; hexokinase; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version

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