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    ITGAV integrin subunit alpha V [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008956, updated on 3-Apr-2024

    Summary

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    Gene symbol
    ITGAV
    Gene description
    integrin subunit alpha V
    See related
    Ensembl:ENSOCUG00000017626
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 7 NC_067380.1 (46529484..46634330, complement)

    Chromosome 7 - NC_067380.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC127491893 Neighboring gene family with sequence similarity 171 member B Neighboring gene zinc finger CCCH-type containing 15 Neighboring gene gamma-aminobutyric acid receptor-associated protein-like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067380.1 Chromosome 7 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The size of sinusoidal fenestrae is a critical determinant of hepatocyte transduction after adenoviral gene transfer. Lievens J, et al. Gene Ther, 2004 Oct. PMID 15269718

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-V
    Names
    alpha-v integrin
    integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067380.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      46529484..46634330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002712329.3 → XP_002712375.1  integrin alpha-V isoform X1

      UniProtKB/TrEMBL
      A0A5F9D0E2, A0A5F9DC35
      Related
      ENSOCUP00000039361.1
      Conserved Domains (4) summary
      smart00191
      Location:365 → 420
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:466 → 913
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:220 → 270
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
      sd00039
      Location:50 → 119
      7WD40; WD40 repeat [structural motif]

    2. XM_051849370.1 → XP_051705330.1  integrin alpha-V isoform X2

    Nucleotide Protein
    Heading Accession and Version

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