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    SOX9 SRY-box transcription factor 9 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008944, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SOX9
    Gene description
    SRY-box transcription factor 9
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 19 NC_067392.1 (53309012..53312153)

    Chromosome 19 - NC_067392.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC103351608 Neighboring gene uncharacterized LOC103351609 Neighboring gene solute carrier family 39 member 11 Neighboring gene somatostatin receptor 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067392.1 Chromosome 19 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parathyroid hormone promotes cartilage healing after free reduction of mandibular condylar fractures by upregulating Sox9. Jia Y, et al. Exp Biol Med (Maywood), 2021 Nov. PMID 34233524, Free PMC Article
    2. Sox9 gene transfer enhanced regenerative effect of bone marrow mesenchymal stem cells on the degenerated intervertebral disc in a rabbit model. Sun W, et al. PLoS One, 2014. PMID 24691466, Free PMC Article
    3. Expression profiles of SRY and SOX9 in rabbit gonads: the classical model of mammalian sex differentiation. Díaz-Hernández V, et al. Sex Dev, 2008. PMID 18769075

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Parathyroid hormone promotes cartilage healing after free reduction of mandibular condylar fractures by upregulating Sox9.
      Title: Parathyroid hormone promotes cartilage healing after free reduction of mandibular condylar fractures by upregulating Sox9.
    2. Sox9 gene transfer could significantly enhance the repair effect of bone marrow mesenchymal stem cells on the degenerated discs.
      Title: Sox9 gene transfer enhanced regenerative effect of bone marrow mesenchymal stem cells on the degenerated intervertebral disc in a rabbit model.
    3. The patterns of SRY/SOX9 expression associated with the process of gonadal morphogenesis in rabbit appear similar to those of other mammals, including humans.
      Title: Expression profiles of SRY and SOX9 in rabbit gonads: the classical model of mammalian sex differentiation.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chondrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in morphogenesis of an epithelium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of chondrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor SOX-9
    Names
    SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)
    SRY-box 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067392.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      53309012..53312153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051825911.1 → XP_051681871.1  transcription factor SOX-9

    Nucleotide Protein
    Heading Accession and Version

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