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    KCNB1 potassium voltage-gated channel subfamily B member 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008779, updated on 8-Mar-2024

    Summary

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    Gene symbol
    KCNB1
    Gene description
    potassium voltage-gated channel subfamily B member 1
    See related
    Ensembl:ENSOCUG00000024174
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    Shab
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 4 NC_067377.1 (384178..488543)

    Chromosome 4 - NC_067377.1Genomic Context describing neighboring genes Neighboring gene beta-1,4-galactosyltransferase 5 Neighboring gene prostaglandin I2 synthase Neighboring gene uncharacterized LOC103352391 Neighboring gene small nucleolar SNORD12/SNORD106 Neighboring gene small nucleolar SNORD12/SNORD106

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067377.1 Chromosome 4 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Contribution of Kv2.1 channels to the delayed rectifier current in freshly dispersed smooth muscle cells from rabbit urethra. Kyle B, et al. Am J Physiol Cell Physiol, 2011 Nov. PMID 21813710, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Analysis of the data suggested that Kv2.1 channels contribute significantly to the voltage-gated potassium current in smooth muscle cells from rabbit urethra.
      Title: Contribution of Kv2.1 channels to the delayed rectifier current in freshly dispersed smooth muscle cells from rabbit urethra.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated potassium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    potassium voltage-gated channel subfamily B member 1
    Names
    potassium voltage-gated channel, Shab-related subfamily, member 1
    voltage-gated potassium channel Kv2.1
    voltage-gated potassium channel subunit Kv2.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082087.1 → NP_001075556.1  potassium voltage-gated channel subfamily B member 1

      See identical proteins and their annotated locations for NP_001075556.1

      Status: PROVISIONAL

      Source sequence(s)
      AF266507
      UniProtKB/Swiss-Prot
      Q9MZ19
      Related
      ENSOCUP00000017212.1, ENSOCUT00000015624.2
      Conserved Domains (5) summary
      smart00225
      Location:33 → 139
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00520
      Location:226 → 424
      Ion_trans; Ion transport protein
      pfam02214
      Location:33 → 132
      BTB_2; BTB/POZ domain
      pfam03521
      Location:467 → 679
      Kv2channel; Kv2 voltage-gated K+ channel
      pfam07885
      Location:337 → 418
      Ion_trans_2; Ion channel

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067377.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      384178..488543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051844879.1 → XP_051700839.1  potassium voltage-gated channel subfamily B member 1 isoform X1

      UniProtKB/TrEMBL
      G1TJT3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MZ19.1 GenPept UniProtKB/Swiss-Prot:Q9MZ19

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