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    Hspa8 heat shock protein 8 [ Mus musculus (house mouse) ]

    Gene ID: 15481, updated on 27-Jun-2015
    Official Symbol
    Hspa8provided by MGI
    Official Full Name
    heat shock protein 8provided by MGI
    Primary source
    MGI:MGI:105384
    See related
    Ensembl:ENSMUSG00000015656; Vega:OTTMUSG00000030238
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; 2410008N15Rik
    Orthologs
    See Hspa8 in Epigenomics, MapViewer
    Location:
    9 A5.1; 9 21.55 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (40801273..40805199)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (40609356..40613282)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene CXADR-like membrane protein Neighboring gene predicted gene, 38622 Neighboring gene predicted gene 16096 Neighboring gene small nucleolar RNA, C/D box 14C Neighboring gene small nucleolar RNA, C/D box 14D Neighboring gene small nucleolar RNA, C/D box 14E Neighboring gene RIKEN cDNA 4931429I11 gene Neighboring gene brain specific homeobox Neighboring gene ubiquitin specific peptidase 10 pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Clone Names

    • MGC102007, MGC106514, MGC118485

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ADP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase activity, coupled IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATPase activity, coupled ISO
    Inferred from Sequence Orthology
    more info
     
    C3HC4-type RING finger domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    G-protein coupled receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    MHC class II protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    heat shock protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    poly(A) RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    unfolded protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    unfolded protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ATP metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    chaperone mediated protein folding requiring cofactor IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    chaperone mediated protein folding requiring cofactor ISO
    Inferred from Sequence Orthology
    more info
     
    chaperone-mediated protein folding ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin coat disassembly IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of fibril organization ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein folding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein refolding ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Prp19 complex ISO
    Inferred from Sequence Orthology
    more info
     
    blood microparticle ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    messenger ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    terminal bouton ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    heat shock cognate 71 kDa protein
    Names
    heat shock cognate 71 kDa protein
    heat shock 70 kDa protein 8
    heat shock 70kD protein 8
    heat shock cognate hsc73
    heat shock protein cognate 70

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031165.4NP_112442.2  heat shock cognate 71 kDa protein

      See identical proteins and their annotated locations for NP_112442.2

      Status: PROVISIONAL

      Source sequence(s)
      AK151775
      Consensus CDS
      CCDS23083.1
      UniProtKB/Swiss-Prot
      P63017
      Related
      ENSMUSP00000015800, OTTMUSP00000039133, ENSMUST00000015800, OTTMUST00000074856
      Conserved Domains (2) summary
      cd10233
      Location:6381
      HSPA1-2_6-8-like_NBD; Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins
      PTZ00009
      Location:1613
      PTZ00009; heat shock 70 kDa protein; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

      Range
      40801273..40805199
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000031.1 Alternate Mm_Celera

      Range
      38034609..38038251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)