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    Wdr47 WD repeat domain 47 [ Mus musculus (house mouse) ]

    Gene ID: 99512, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Wdr47provided by MGI
    Official Full Name
    WD repeat domain 47provided by MGI
    Primary source
    MGI:MGI:2139593
    See related
    Ensembl:ENSMUSG00000040389 AllianceGenome:MGI:2139593
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0893; 1810073M12Rik
    Summary
    Predicted to be located in cytoplasm. Is expressed in nervous system; sensory organ; and vibrissa. Orthologous to human WDR47 (WD repeat domain 47). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 32.5), CNS E14 (RPKM 23.3) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Wdr47 in Genome Data Viewer
    Location:
    3 F3; 3 47.38 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (108498302..108553035)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (108591223..108645719)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:108365309-108365496 Neighboring gene STARR-positive B cell enhancer ABC_E3459 Neighboring gene transmembrane protein 167B Neighboring gene STARR-positive B cell enhancer ABC_E1629 Neighboring gene STARR-positive B cell enhancer ABC_E6105 Neighboring gene TATA-box binding protein associated factor 13 Neighboring gene 40S ribosomal protein S23 pseudogene Neighboring gene chloride channel CLIC-like 1 Neighboring gene G-protein signalling modulator 2 (AGS3-like, C. elegans) Neighboring gene STARR-positive B cell enhancer ABC_E4575 Neighboring gene AKNA domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules. Liu H, et al. Nat Commun, 2021 Oct 4. PMID 34608154, Free PMC Article
    2. Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats. Wang W, et al. PLoS One, 2012. PMID 22523538, Free PMC Article
    3. Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins. Chen Y, et al. Cell Rep, 2020 Apr 21. PMID 32320668
    4. WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Kannan M, et al. Proc Natl Acad Sci U S A, 2017 Oct 31. PMID 29078390, Free PMC Article
    5. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Targeted (4)  1 citation
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within adult locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within anterior commissure morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within autophagy IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within autophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within brain development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cerebral cortex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cerebral cortex radial glia-guided migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within corpus callosum development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within detection of hot stimulus involved in thermoception IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within motor behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of microtubule depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within neural precursor cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within neuronal stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in growth cone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    WD repeat-containing protein 47
    Names
    nemitin
    neuronal enriched MAP interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358053.1 → NP_001344982.1  WD repeat-containing protein 47 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL683823
      Conserved Domains (4) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      cd00200
      Location:599 → 915
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:611 → 659
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    2. NM_001358054.1 → NP_001344983.1  WD repeat-containing protein 47 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL683823
      Conserved Domains (5) summary
      smart00667
      Location:9 → 42
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      cd00200
      Location:600 → 868
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:612 → 660
      7WD40; WD40 repeat [structural motif]
      cl26927
      Location:293 → 483
      Activator_LAG-3; Transcriptional activator LAG-3

    3. NM_001358055.1 → NP_001344984.1  WD repeat-containing protein 47 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL683823
      Conserved Domains (5) summary
      smart00667
      Location:9 → 42
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      cd00200
      Location:600 → 868
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:612 → 660
      7WD40; WD40 repeat [structural motif]
      cl26927
      Location:293 → 483
      Activator_LAG-3; Transcriptional activator LAG-3

    4. NM_181400.3 → NP_852065.2  WD repeat-containing protein 47 isoform 1

      See identical proteins and their annotated locations for NP_852065.2

      Status: VALIDATED

      Source sequence(s)
      AL683823
      Consensus CDS
      CCDS17765.1
      UniProtKB/Swiss-Prot
      A2AGC7, Q80TP4, Q8CGF6
      Related
      ENSMUSP00000057482.9, ENSMUST00000051145.15
      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:293 → 483
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:600 → 916
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:612 → 660
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      108498302..108553035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502415.5 → XP_006502478.1  WD repeat-containing protein 47 isoform X9

      See identical proteins and their annotated locations for XP_006502478.1

      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:300 → 490
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:607 → 925
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:619 → 667
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    2. XM_006502414.5 → XP_006502477.1  WD repeat-containing protein 47 isoform X9

      See identical proteins and their annotated locations for XP_006502477.1

      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:300 → 490
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:607 → 925
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:619 → 667
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    3. XM_036163436.1 → XP_036019329.1  WD repeat-containing protein 47 isoform X10

      Conserved Domains (4) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      cd00200
      Location:607 → 923
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:619 → 667
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    4. XM_006502417.5 → XP_006502480.1  WD repeat-containing protein 47 isoform X11

      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:293 → 483
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:600 → 918
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:612 → 660
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    5. XM_011240310.3 → XP_011238612.1  WD repeat-containing protein 47 isoform X12

      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:293 → 482
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:599 → 917
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:611 → 659
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    6. XM_017319818.3 → XP_017175307.1  WD repeat-containing protein 47 isoform X9

      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:300 → 490
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:607 → 925
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:619 → 667
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    7. XM_011240309.3 → XP_011238611.1  WD repeat-containing protein 47 isoform X10

      Conserved Domains (4) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      cd00200
      Location:607 → 923
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:619 → 667
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    8. XM_030252938.2 → XP_030108798.1  WD repeat-containing protein 47 isoform X11

      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:293 → 483
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:600 → 918
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:612 → 660
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    9. XM_017319819.2 → XP_017175308.1  WD repeat-containing protein 47 isoform X13

      UniProtKB/Swiss-Prot
      A2AGC7, Q80TP4, Q8CGF6
      Conserved Domains (5) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:293 → 483
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:600 → 916
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:612 → 660
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    10. XM_036163437.1 → XP_036019330.1  WD repeat-containing protein 47 isoform X14

      Conserved Domains (4) summary
      smart00668
      Location:45 → 102
      CTLH; C-terminal to LisH motif
      cd00200
      Location:599 → 915
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:611 → 659
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:13 → 40
      LisH_TPL; LisH-like dimerisation domain

    11. XM_030252937.2 → XP_030108797.1  WD repeat-containing protein 47 isoform X8

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:343 → 532
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:649 → 965
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:661 → 709
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    12. XM_030252939.2 → XP_030108799.1  WD repeat-containing protein 47 isoform X15

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:350 → 540
      Activator_LAG-3; Transcriptional activator LAG-3
      sd00039
      Location:668 → 715
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain
      cl29593
      Location:657 → 756
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    13. XM_030252932.1 → XP_030108792.1  WD repeat-containing protein 47 isoform X1

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:350 → 540
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:657 → 975
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:669 → 717
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    14. XM_030252933.2 → XP_030108793.1  WD repeat-containing protein 47 isoform X3

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:350 → 540
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:657 → 973
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:669 → 717
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    15. XM_011240308.2 → XP_011238610.2  WD repeat-containing protein 47 isoform X2

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:350 → 539
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:656 → 974
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:668 → 716
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    16. XM_036163435.1 → XP_036019328.1  WD repeat-containing protein 47 isoform X4

      Conserved Domains (4) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      cd00200
      Location:656 → 972
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:668 → 716
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    17. XM_030252934.1 → XP_030108794.1  WD repeat-containing protein 47 isoform X5

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:343 → 533
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:650 → 968
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:662 → 710
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    18. XM_030252936.2 → XP_030108796.1  WD repeat-containing protein 47 isoform X7

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:343 → 533
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:650 → 966
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:662 → 710
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    19. XM_030252935.1 → XP_030108795.1  WD repeat-containing protein 47 isoform X6

      Conserved Domains (5) summary
      smart00668
      Location:95 → 152
      CTLH; C-terminal to LisH motif
      pfam11498
      Location:343 → 532
      Activator_LAG-3; Transcriptional activator LAG-3
      cd00200
      Location:649 → 967
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:661 → 709
      7WD40; WD40 repeat [structural motif]
      pfam17814
      Location:63 → 90
      LisH_TPL; LisH-like dimerisation domain

    RNA

    1. XR_004941418.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CGF6.2 GenPept UniProtKB/Swiss-Prot:Q8CGF6

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